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Free Practice Questions for Tamil Nadu HSE Second Year Biochemistry

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Exam Review

Key Facts: Tamil Nadu HSE Second Year Biochemistry Exam

10:00–1:15

Official March 2026 HSE+2 theory sitting window including reading/verification time (dge.tn.gov.in timetable)

DGE TN HSE+2 March 2026 public examination timetable

35/100

Minimum pass mark per subject under the HSE new pattern, subject to theory/practical floor rules

DGE HSE_E.pdf scheme of examination

3 hours

Approximate theory writing duration after reading and particulars verification in the public exam schedule

DGE TN HSE+2 March 2026 timetable

DGE TN

Administered by the Directorate of Government Examinations, Chennai, for Tamil Nadu State Board Higher Secondary

dge.tn.gov.in

SCERT syllabus

Class 12 textbooks and syllabus prescribed by SCERT / School Education Department (Samacheer Kalvi)

DGE HSE scheme — syllabus prescribed by SCERT/DSE

English MCQ bank

This practice set is an English-language MCQ study adaptation, not the official mixed written paper

OpenExamPrep practice-content policy

₹150/₹200

School exam fee band for groups without/with practical subjects plus certificate/service charges (concessions apply)

DGE HSE_E.pdf school candidate fee table

March 2026

HSE Second Year public theory examinations scheduled 2–26 March 2026 with practicals 9–14 February 2026

DGE TN official timetable PDF 04.11.2025

Free English MCQ practice for Tamil Nadu HSE +2 Biochemistry (DGE). Official paper is mixed written theory on the Samacheer Kalvi Class 12 syllabus — this bank is a study adaptation, not a format simulation.

Sample Tamil Nadu HSE Second Year Biochemistry Practice Questions

Try these sample questions to review concepts for the Tamil Nadu HSE Second Year Biochemistry exam. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1Which monosaccharide is the primary blood sugar used by human tissues for energy?
A.Fructose
B.Galactose
C.Glucose
D.Ribose
Explanation: Glucose is the main circulating monosaccharide and the preferred fuel for brain and red blood cells under normal conditions. Fructose and galactose are largely converted to glucose or glycolytic intermediates in the liver.
2Sucrose is a disaccharide composed of which pair of monosaccharides?
A.Glucose and glucose
B.Glucose and galactose
C.Glucose and fructose
D.Galactose and fructose
Explanation: Sucrose (table sugar) consists of α-D-glucose linked to β-D-fructose by an α,β-1,2-glycosidic bond. Lactose is glucose + galactose; maltose is two glucose units.
3Starch and glycogen are both polymers of glucose. The major structural difference is that glycogen has:
A.β-1,4 linkages instead of α-1,4
B.More frequent α-1,6 branch points
C.No reducing ends
D.Only amylose-type unbranched chains
Explanation: Both starch (amylopectin) and glycogen use α-1,4 chains with α-1,6 branches. Glycogen is more highly branched (about every 8–12 residues) than amylopectin (about every 24–30 residues), which increases solubility and mobilization rate.
4Which test is classically used to distinguish reducing sugars from non-reducing sugars?
A.Biuret test
B.Benedict's (or Fehling's) test
C.Seliwanoff's test only
D.Molisch test only
Explanation: Benedict's and Fehling's reagents detect free aldehyde (or tautomerizable) groups that reduce Cu²⁺ to Cu₂O. Sucrose is non-reducing until hydrolyzed; glucose, fructose, maltose, and lactose give positive reducing-sugar tests.
5The general formula for many simple carbohydrates is:
A.CnH2n+2On
B.Cn(H2O)n
C.CnH2nOn−2
D.CnH2nO2
Explanation: Historically, carbohydrates were defined as hydrates of carbon with the empirical formula Cn(H2O)n (e.g., glucose C6H12O6). Modern definitions focus on polyhydroxy aldehydes/ketones and their derivatives; some sugars deviate slightly from this simple ratio.
6Cellulose differs from starch primarily because cellulose contains:
A.α-1,4 glycosidic linkages only
B.β-1,4 glycosidic linkages
C.α-1,6 linkages exclusively
D.Peptide bonds between glucose units
Explanation: Cellulose is a linear polymer of β-D-glucose units joined by β-1,4 glycosidic bonds, forming rigid fibrils. Humans lack cellulase, so cellulose is dietary fiber rather than an energy source.
7The basic building blocks of proteins are:
A.Monosaccharides
B.Fatty acids
C.Amino acids
D.Nucleotides
Explanation: Proteins are polymers of α-amino acids linked by peptide bonds. Monosaccharides build carbohydrates, fatty acids (with glycerol) build many lipids, and nucleotides build nucleic acids.
8Which functional groups are present in every standard α-amino acid used in proteins (at physiological pH forms aside)?
A.Only a carboxyl group
B.An amino group and a carboxyl group attached to the α-carbon
C.Only a sulfhydryl group
D.A phosphate and a hydroxyl group
Explanation: Standard α-amino acids have a central α-carbon bonded to a hydrogen, a side chain (R), an amino group, and a carboxyl group. The R group confers chemical diversity among the 20 common amino acids.
9The peptide bond in proteins is best described as:
A.An ester linkage between two carboxyl groups
B.An amide linkage formed between the carboxyl of one amino acid and the amino group of the next
C.A glycosidic bond
D.A phosphodiester bond
Explanation: A peptide bond is a covalent amide bond created by condensation between the α-carboxyl of one amino acid and the α-amino group of another, releasing water. It has partial double-bond character and is planar.
10Which level of protein structure describes the overall three-dimensional fold of a single polypeptide chain?
A.Primary structure
B.Secondary structure
C.Tertiary structure
D.Quaternary structure
Explanation: Tertiary structure is the complete 3D arrangement of one polypeptide, stabilized by hydrophobic interactions, hydrogen bonds, ionic interactions, and disulfide bridges. Primary is sequence; secondary is local folds (α-helix, β-sheet); quaternary is multi-subunit assembly.

About the Tamil Nadu HSE Second Year Biochemistry Exam

Tamil Nadu HSE Second Year Biochemistry is the Class 12 public examination subject paper in Bio-Chemistry under DGE Tamil Nadu. It assesses SCERT/Samacheer Kalvi Class 12 learning outcomes for this subject. Official assessment is a mixed written theory paper (with practical and internal components where applicable) totaling 100 marks per subject. Listed as BIO-CHEMISTRY on DGE timetable; theory with practical lab components. Use this free English MCQ bank to build concept fluency before the March public exams.

Exam sponsor: Directorate of Government Examinations (DGE), Tamil Nadu. The requirements and fees below concern the certification or admission exam, separate from our free practice resources.

Assessment

Official Tamil Nadu HSE Second Year (+2) public examination paper in Bio-Chemistry, administered by DGE Tamil Nadu. March 2026 theory window: 02.03.2026–26.03.2026; practical window for +2: 09.02.2026–14.02.2026 (official timetable). Each theory sitting runs 10:00 a.m.–1:15 p.m. including question-paper reading and particulars verification (about 3 hours writing after reading). For subjects with practical: theory is commonly assessed out of 70 marks (minimum 15 in theory) with practical attendance required, internal assessment contributing to the 100-mark subject total. Official assessment is mixed written format (short/long/structured items per the year's blueprint), not pure MCQ. Listed as BIO-CHEMISTRY on DGE timetable; theory with practical lab components. Syllabus and textbooks are prescribed by SCERT / Director of School Education (Samacheer Kalvi Class 12). This site's bank is an English-language multiple-choice study adaptation for concept fluency — not an official translation, format simulation, or substitute for writing, practical, project, or oral evidence.

Time Limit

Official theory sitting 10:00 a.m.–1:15 p.m. (about 3 hours writing after reading/verification) per March 2026 DGE timetable

Passing Score

Minimum 35 out of 100 per subject overall under the new 600-mark HSE pattern (HSE_E.pdf), with additional floors: theory minimum 15/70 and must appear for practical for practical-bearing subjects. Confirm the current DGE result rules for your candidate category.

Exam / Certification Fees

School candidates: DGE HSE scheme lists examination fee ₹200 for groups with practical subjects, plus Mark Certificate ₹20 and Service Charges ₹5 (Tamil-medium candidates and notified concession categories are often fee-exempt). Private (H) candidates: per-subject fees as notified (scheme text commonly cites subject + registration/mark/service components). Confirm current-session circulars on dge.tn.gov.in — fee tables can be updated by notification.

Exam sponsor website

Fees, eligibility, and exam policies can change. Confirm them with the exam sponsor before applying or paying.

Our practice resources: topics covered

We aim to reflect publicly available exam outlines and topic information in our study resources. Coverage, format, and difficulty may differ from the actual exam, and we cannot guarantee that every detail is accurate or current. Confirm exam requirements, fees, and policies with the official exam sponsor.

30%

Biomolecules Structure and Function

Carbohydrates, proteins, lipids, nucleic acids, and vitamins.

30%

Enzymes and Metabolism

Enzyme kinetics and major metabolic pathways at Class 12 depth.

25%

Clinical and Nutritional Biochemistry

Blood, hormones, nutrition biochemistry, and clinical markers basics.

15%

Lab Techniques and Instrumentation

pH, chromatography, spectroscopy, and lab safety concepts.

Preparing for the Tamil Nadu HSE Second Year Biochemistry Exam

What You Need to Know

  • Passing score: Minimum 35 out of 100 per subject overall under the new 600-mark HSE pattern (HSE_E.pdf), with additional floors: theory minimum 15/70 and must appear for practical for practical-bearing subjects. Confirm the current DGE result rules for your candidate category.
  • Assessment: Official Tamil Nadu HSE Second Year (+2) public examination paper in Bio-Chemistry, administered by DGE Tamil Nadu. March 2026 theory window: 02.03.2026–26.03.2026; practical window for +2: 09.02.2026–14.02.2026 (official timetable). Each theory sitting runs 10:00 a.m.–1:15 p.m. including question-paper reading and particulars verification (about 3 hours writing after reading). For subjects with practical: theory is commonly assessed out of 70 marks (minimum 15 in theory) with practical attendance required, internal assessment contributing to the 100-mark subject total. Official assessment is mixed written format (short/long/structured items per the year's blueprint), not pure MCQ. Listed as BIO-CHEMISTRY on DGE timetable; theory with practical lab components. Syllabus and textbooks are prescribed by SCERT / Director of School Education (Samacheer Kalvi Class 12). This site's bank is an English-language multiple-choice study adaptation for concept fluency — not an official translation, format simulation, or substitute for writing, practical, project, or oral evidence.
  • Time limit: Official theory sitting 10:00 a.m.–1:15 p.m. (about 3 hours writing after reading/verification) per March 2026 DGE timetable
  • Exam / certification fees: School candidates: DGE HSE scheme lists examination fee ₹200 for groups with practical subjects, plus Mark Certificate ₹20 and Service Charges ₹5 (Tamil-medium candidates and notified concession categories are often fee-exempt). Private (H) candidates: per-subject fees as notified (scheme text commonly cites subject + registration/mark/service components). Confirm current-session circulars on dge.tn.gov.in — fee tables can be updated by notification. Official sources

Using Our Practice Resources

  • Work through all 100 available questions
  • Review every answer and explanation
  • Track weak areas and revisit them
  • Use our AI tutor for tough concepts

Tamil Nadu HSE Second Year Biochemistry: Suggested Study Strategy

1Study from the current SCERT / Samacheer Kalvi Class 12 Biochemistry textbooks and the year's model question paper pattern released for DGE public exams.
2Practise both conceptual MCQs and the official long/short answer formats; this bank cannot replace writing or practical skill evidence.
3For calculation-heavy units, rework numerical problems with units and significant figures as used in the textbook examples.
4Use the official timetable to plan revision around your specific Part I / II / III sitting dates.
5After each practice set, log weak topic areas (by unit) and re-read those textbook chapters before retesting.

Frequently Asked Questions

What is the Tamil Nadu HSE Second Year Biochemistry exam?

It is the official Class 12 (Higher Secondary Second Year / +2) public examination paper in Bio-Chemistry, conducted by the Directorate of Government Examinations (DGE), Tamil Nadu, under the State Board / Samacheer Kalvi syllabus.

How long is the official theory paper?

The March 2026 timetable schedules each theory sitting from 10:00 a.m. to 1:15 p.m., including question-paper reading and candidate particulars verification before the main writing period.

What is the passing score?

Minimum 35 out of 100 per subject overall under the new 600-mark HSE pattern (HSE_E.pdf), with additional floors: theory minimum 15/70 and must appear for practical for practical-bearing subjects. Confirm the current DGE result rules for your candidate category.

Is this practice bank the same format as the official paper?

No. Official papers use mixed written formats (and practicals where applicable). These 100 questions are an English-language multiple-choice study adaptation for knowledge and judgment practice only.

Where can I find the official timetable and scheme?

Download the public examination timetable and HSE scheme documents from the Directorate of Government Examinations website (dge.tn.gov.in), including the March 2026 HSE+2 timetable PDF.