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100+ Free Tamil Nadu HSE Second Year Biochemistry Practice Questions

Tamil Nadu Higher Secondary Second Year (HSE +2 / Class 12) Bio-Chemistry under the Directorate of Government Examinations (DGE), Tamil Nadu practice questions are available now; exam metadata is being verified.

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2026 Statistics

Key Facts: Tamil Nadu HSE Second Year Biochemistry Exam

10:00–1:15

Official March 2026 HSE+2 theory sitting window including reading/verification time (dge.tn.gov.in timetable)

DGE TN HSE+2 March 2026 public examination timetable

35/100

Minimum pass mark per subject under the HSE new pattern, subject to theory/practical floor rules

DGE HSE_E.pdf scheme of examination

3 hours

Approximate theory writing duration after reading and particulars verification in the public exam schedule

DGE TN HSE+2 March 2026 timetable

DGE TN

Administered by the Directorate of Government Examinations, Chennai, for Tamil Nadu State Board Higher Secondary

dge.tn.gov.in

SCERT syllabus

Class 12 textbooks and syllabus prescribed by SCERT / School Education Department (Samacheer Kalvi)

DGE HSE scheme — syllabus prescribed by SCERT/DSE

English MCQ bank

This practice set is an English-language MCQ study adaptation, not the official mixed written paper

OpenExamPrep practice-content policy

₹150/₹200

School exam fee band for groups without/with practical subjects plus certificate/service charges (concessions apply)

DGE HSE_E.pdf school candidate fee table

March 2026

HSE Second Year public theory examinations scheduled 2–26 March 2026 with practicals 9–14 February 2026

DGE TN official timetable PDF 04.11.2025

Free English MCQ practice for Tamil Nadu HSE +2 Biochemistry (DGE). Official paper is mixed written theory on the Samacheer Kalvi Class 12 syllabus — this bank is a study adaptation, not a format simulation.

Sample Tamil Nadu HSE Second Year Biochemistry Practice Questions

Try these sample questions to test your Tamil Nadu HSE Second Year Biochemistry exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1Which monosaccharide is the primary blood sugar used by human tissues for energy?
A.Fructose
B.Galactose
C.Glucose
D.Ribose
Explanation: Glucose is the main circulating monosaccharide and the preferred fuel for brain and red blood cells under normal conditions. Fructose and galactose are largely converted to glucose or glycolytic intermediates in the liver.
2Sucrose is a disaccharide composed of which pair of monosaccharides?
A.Glucose and glucose
B.Glucose and galactose
C.Glucose and fructose
D.Galactose and fructose
Explanation: Sucrose (table sugar) consists of α-D-glucose linked to β-D-fructose by an α,β-1,2-glycosidic bond. Lactose is glucose + galactose; maltose is two glucose units.
3Starch and glycogen are both polymers of glucose. The major structural difference is that glycogen has:
A.β-1,4 linkages instead of α-1,4
B.More frequent α-1,6 branch points
C.No reducing ends
D.Only amylose-type unbranched chains
Explanation: Both starch (amylopectin) and glycogen use α-1,4 chains with α-1,6 branches. Glycogen is more highly branched (about every 8–12 residues) than amylopectin (about every 24–30 residues), which increases solubility and mobilization rate.
4Which test is classically used to distinguish reducing sugars from non-reducing sugars?
A.Biuret test
B.Benedict's (or Fehling's) test
C.Seliwanoff's test only
D.Molisch test only
Explanation: Benedict's and Fehling's reagents detect free aldehyde (or tautomerizable) groups that reduce Cu²⁺ to Cu₂O. Sucrose is non-reducing until hydrolyzed; glucose, fructose, maltose, and lactose give positive reducing-sugar tests.
5The general formula for many simple carbohydrates is:
A.CnH2n+2On
B.Cn(H2O)n
C.CnH2nOn−2
D.CnH2nO2
Explanation: Historically, carbohydrates were defined as hydrates of carbon with the empirical formula Cn(H2O)n (e.g., glucose C6H12O6). Modern definitions focus on polyhydroxy aldehydes/ketones and their derivatives; some sugars deviate slightly from this simple ratio.
6Cellulose differs from starch primarily because cellulose contains:
A.α-1,4 glycosidic linkages only
B.β-1,4 glycosidic linkages
C.α-1,6 linkages exclusively
D.Peptide bonds between glucose units
Explanation: Cellulose is a linear polymer of β-D-glucose units joined by β-1,4 glycosidic bonds, forming rigid fibrils. Humans lack cellulase, so cellulose is dietary fiber rather than an energy source.
7The basic building blocks of proteins are:
A.Monosaccharides
B.Fatty acids
C.Amino acids
D.Nucleotides
Explanation: Proteins are polymers of α-amino acids linked by peptide bonds. Monosaccharides build carbohydrates, fatty acids (with glycerol) build many lipids, and nucleotides build nucleic acids.
8Which functional groups are present in every standard α-amino acid used in proteins (at physiological pH forms aside)?
A.Only a carboxyl group
B.An amino group and a carboxyl group attached to the α-carbon
C.Only a sulfhydryl group
D.A phosphate and a hydroxyl group
Explanation: Standard α-amino acids have a central α-carbon bonded to a hydrogen, a side chain (R), an amino group, and a carboxyl group. The R group confers chemical diversity among the 20 common amino acids.
9The peptide bond in proteins is best described as:
A.An ester linkage between two carboxyl groups
B.An amide linkage formed between the carboxyl of one amino acid and the amino group of the next
C.A glycosidic bond
D.A phosphodiester bond
Explanation: A peptide bond is a covalent amide bond created by condensation between the α-carboxyl of one amino acid and the α-amino group of another, releasing water. It has partial double-bond character and is planar.
10Which level of protein structure describes the overall three-dimensional fold of a single polypeptide chain?
A.Primary structure
B.Secondary structure
C.Tertiary structure
D.Quaternary structure
Explanation: Tertiary structure is the complete 3D arrangement of one polypeptide, stabilized by hydrophobic interactions, hydrogen bonds, ionic interactions, and disulfide bridges. Primary is sequence; secondary is local folds (α-helix, β-sheet); quaternary is multi-subunit assembly.

About the Tamil Nadu HSE Second Year Biochemistry Practice Questions

Verified exam format metadata for Tamil Nadu Higher Secondary Second Year (HSE +2 / Class 12) Bio-Chemistry under the Directorate of Government Examinations (DGE), Tamil Nadu is pending. The practice questions above remain available while official exam length, timing, passing score, fee, and administrator details are reviewed.