100+ Free RANZCR Pathology Practice Questions
Pass your RANZCR Clinical Radiology Phase 2 - Pathology exam on the first try — instant access, no signup required.
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Sample RANZCR Pathology Practice Questions
Try these sample questions to test your RANZCR Pathology exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.
1A 12-year-old with multiple café-au-lait macules and axillary freckling undergoes MRI showing optic pathway glioma. Which inherited disorder is most likely?
2Renal angiomyolipomas and cortical tubers on MRI in a young adult most strongly suggest which diagnosis?
3Bilateral cerebellar haemangioblastomas and a pancreatic neuroendocrine tumour in a 35-year-old suggest mutation of which gene?
4Medullary thyroid carcinoma, phaeochromocytoma, and parathyroid hyperplasia in one patient indicate which syndrome?
5Osteogenesis imperfecta is primarily caused by defective synthesis of which structural protein?
6In an IDH-wildtype diffuse astrocytic glioma, which histological finding is sufficient to support a diagnosis of glioblastoma, CNS WHO grade 4?
7A diffuse glioma is IDH-mutant and has whole-arm 1p/19q codeletion. Which integrated diagnosis is supported?
8Ring-enhancing lesions with central necrosis in an immunocompromised patient most commonly represent which pathology?
9Demyelinating plaques in multiple sclerosis show perivenular inflammation and loss of which stained structure?
10A cystic cerebellar tumour with an enhancing mural nodule in a child is most consistent with which diagnosis?
About the RANZCR Pathology Exam
The RANZCR Clinical Radiology Phase 2 Pathology examination is one of three Phase 2 written papers (with Clinical Radiology MCQ and Case Reporting) that clinical radiology trainees in Australia and New Zealand must pass before sitting the OSCER. The 3-hour paper tests applied general pathology as it relates to imaging interpretation across nine topic areas, through 100 multiple choice questions and 10 short answer questions. Questions assess recognition of pathological consequences of disease, morphological changes associated with therapies, and occupational exposures. It is offered twice yearly, typically in January and July.
Assessment
One 3-hour written paper: 100 MCQs (single best answer, 1 mark each, 100 marks) and 10 short answer questions (6 marks each, 60 marks), for 160 marks total. From sitting 1, 2026, MCQs have four answer options instead of five. Delivered twice a year at invigilated Clifton venues. The MCQ section may include pictorial multiple-choice questions (PMQs) with images.
Time Limit
3 hours.
Passing Score
Standard-set for each sitting; RANZCR does not publish a fixed numerical pass mark. Trainees must pass all three Phase 2 written components (Pathology, Radiology MCQ, and Case Reporting) before sitting the OSCER.
Exam Fee
Phase 2 written component fees are published annually on the RANZCR Fees page; each of the three Phase 2 written papers is charged separately. Fees are reviewed annually by RANZCR. (Royal Australian and New Zealand College of Radiologists (RANZCR))
RANZCR Pathology Exam Content Outline
Genetic Syndromes / Multi-system Conditions
Inherited tumour syndromes, connective tissue disorders, and multi-system conditions with characteristic imaging-pathological correlates.
Brain
CNS neoplasms, demyelination, infection, vascular pathology, neurodegeneration, and congenital malformations.
Head and Neck
Salivary gland, thyroid, sinonasal pathology, squamous cell carcinoma, and skull base lesions.
Spine
Disc degeneration, infection, neoplasms, metabolic bone disease, and cord compression.
Cardiothoracic
Lung neoplasms, interstitial lung disease, pleural pathology, mediastinal masses, and cardiac pathology.
Abdomen and Pelvis
Hepatobiliary, pancreatic, gastrointestinal, renal, and adrenal pathology.
Musculoskeletal
Bone tumours, arthritis, metabolic bone disease, soft tissue tumours, and fracture healing.
Breast
Benign and malignant breast lesions, calcification patterns, and post-treatment changes.
Obstetrics and Gynecology
Placental pathology, gestational trophoblastic disease, and ovarian and uterine neoplasms.
How to Pass the RANZCR Pathology Exam
What You Need to Know
- Passing score: Standard-set for each sitting; RANZCR does not publish a fixed numerical pass mark. Trainees must pass all three Phase 2 written components (Pathology, Radiology MCQ, and Case Reporting) before sitting the OSCER.
- Assessment: One 3-hour written paper: 100 MCQs (single best answer, 1 mark each, 100 marks) and 10 short answer questions (6 marks each, 60 marks), for 160 marks total. From sitting 1, 2026, MCQs have four answer options instead of five. Delivered twice a year at invigilated Clifton venues. The MCQ section may include pictorial multiple-choice questions (PMQs) with images.
- Time limit: 3 hours.
- Exam fee: Phase 2 written component fees are published annually on the RANZCR Fees page; each of the three Phase 2 written papers is charged separately. Fees are reviewed annually by RANZCR.
Keys to Passing
- Complete 500+ practice questions
- Score 80%+ consistently before scheduling
- Focus on highest-weighted sections
- Use our AI tutor for tough concepts
RANZCR Pathology Study Tips from Top Performers
Frequently Asked Questions
What is the RANZCR Pathology exam?
The Pathology exam is one of the three RANZCR Clinical Radiology Phase 2 written papers (alongside Clinical Radiology MCQ and Case Reporting). It is a 3-hour paper testing applied general pathology as it relates to imaging interpretation, through 100 multiple choice questions and 10 short answer questions.
What is the pass mark for the RANZCR Pathology exam?
RANZCR does not publish a fixed numerical pass mark. The standard is set individually for each sitting using formal standard-setting procedures. All three Phase 2 written papers must be passed before a trainee is eligible to sit the OSCER.
How often is the RANZCR Pathology exam held?
The Pathology paper is offered twice a year, typically in January and July, at invigilated Clifton venues in Australia, New Zealand, and Singapore, delivered via the risr/assess platform.
What topics does the Pathology exam cover?
The Pathology curriculum covers nine topic areas with approximate weightings: Genetic Syndromes (5%), Brain (15%), Head and Neck (15%), Spine (5%), Cardiothoracic (15%), Abdomen and Pelvis (20%), Musculoskeletal (5%), Breast (5%), and Obstetrics and Gynecology (15%). RANZCR notes these percentages are approximate and may vary slightly between sittings.
Are there images in the RANZCR Pathology exam?
Yes. The MCQ section can include pictorial multiple-choice questions (PMQs) with images; RANZCR's 2026 Sitting 1 report describes a mix of text-based SBAs and PMQs. This free practice bank uses text-based stems.