Free CRNI® Exam Flashcards

Memorize 50 essential terms and definitions for the Certified Registered Nurse Infusion (CRNI®) Examination. See the term, recall the definition, then flip to check yourself.

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Vessel health and preservation assessment

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Card 1 of 50Principles: Anatomy & Physiology

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About These CRNI® Flashcards

These 50 flashcards are designed to help you memorize key terms and definitions for the Certified Registered Nurse Infusion (CRNI®) Examination. Each card shows a term on the front and its definition on the back—the classic flashcard format for vocabulary memorization. Use these alongside our practice questions to build both recall and comprehension.

Topics Covered

Principles: Anatomy & Physiology4 cards
Principles: Infection Prevention8 cards
Principles: Phlebotomy3 cards
Access Devices: Technology & Clinical Applications11 cards
Access Devices: Special Populations2 cards
Access Devices: Device-Related Complications3 cards
Infusion Therapies: Pain Management2 cards
Infusion Therapies: Cardiovascular1 cards
Infusion Therapies: Antineoplastic2 cards
Infusion Therapies: Biologics & Immunologic2 cards
Infusion Therapies: Anti-infectives2 cards
Infusion Therapies: Blood Products2 cards
Infusion Therapies: Fluid & Electrolyte Balance4 cards
Infusion Therapies: Parenteral Nutrition3 cards
Infusion Therapies: Therapy-Related Complications1 cards

Complete Flashcard Reference

Review every term in this set. Open any term to reveal its definition.

Vessel health and preservation assessment

Assess the prescribed therapy, expected duration, vascular history, and available vessels before selecting an access device. The goal is safe therapy delivery while preserving future access.

Why does therapy characteristics matter for device selection?

A device must fit the infusate and treatment plan. Irritant or vesicant therapy, expected duration, and required flow can make a short peripheral catheter inappropriate.

Phlebitis: common assessment findings

Look for pain or tenderness, erythema, warmth, swelling, or a palpable venous cord along the vein. Assess promptly and follow the organization’s escalation and device-removal policy.

Why is patient positioning important for vascular access?

Positioning affects vessel visibility, comfort, and procedural safety. Use the procedure-specific position and adjust for the patient’s clinical condition rather than using one position for every insertion or removal.

Standard precautions in infusion care

Use them for every patient. They include hand hygiene and risk-based personal protective equipment when exposure to blood or body fluids is anticipated.

Aseptic non-touch technique

Keep key parts and key sites from being touched after disinfection. If sterility is compromised, correct it before proceeding.

Hand hygiene timing for vascular access

Perform hand hygiene before and after patient contact and before aseptic tasks. Gloves do not replace hand hygiene.

CLABSI prevention: core habit

Every central-line access should use meticulous hand hygiene, aseptic technique, and disinfection of the access point. Preventing contamination is safer than treating a bloodstream infection.

Disinfecting a needleless connector

Use the approved antiseptic and allow it to dry completely before access. Scrubbing without adequate drying can undermine the antiseptic step.

Local versus systemic catheter infection clues

Local findings can include insertion-site erythema, tenderness, or drainage. Fever, chills, or hemodynamic changes raise concern for systemic infection and require prompt assessment and escalation.

Why inspect the dressing and insertion site?

Inspection helps detect moisture, lifting, drainage, bleeding, inflammation, or device migration. A compromised dressing can increase infection and dislodgement risk.

Chain of infection: where can nursing intervene?

Break transmission through hand hygiene, aseptic technique, cleaning and disinfection, appropriate PPE, and timely recognition of infection signs.

Blood culture collection priority

Prevent contamination: verify the order and patient, use the required antiseptic technique, and collect specimens according to the organization’s protocol before antimicrobial therapy when clinically feasible.

Why label specimens at the bedside?

Bedside labeling after patient identification preserves specimen-to-patient accuracy and reduces the risk of a dangerous identification error.

Therapeutic phlebotomy: immediate safety focus

Monitor for dizziness, hypotension, or vasovagal symptoms during and after the prescribed blood removal. Follow the ordered volume, replacement plan, and observation requirements.

Short peripheral IV catheter: best use

Use for appropriate short-term peripheral therapy when the infusate and patient’s veins are suitable. Reassess if the therapy, duration, or vessel condition changes.

Midline catheter: central or peripheral?

A midline is a peripheral device; its tip does not terminate in central circulation. Do not treat it as interchangeable with a central venous access device.

PICC: defining feature

A peripherally inserted central catheter enters through a peripheral vein but terminates in central circulation. It is selected when the therapy and anticipated duration warrant central access.

Tunneled central venous catheter

The catheter travels through a subcutaneous tunnel before entering a central vein. The tunnel and cuff help support longer-term access and securement.

Implanted port

A port is a totally implanted central venous access device. It is accessed through intact skin with a noncoring needle when therapy is needed.

Intraosseous access

Intraosseous access uses the medullary space when rapid vascular access is needed and conventional access is not available. It is a bridge until appropriate vascular access is established.

Subcutaneous infusion

Subcutaneous infusion delivers selected medications or fluids into subcutaneous tissue. Assess the site for pain, leakage, swelling, and local reaction.

Why use a catheter securement device?

Securement limits catheter movement and accidental dislodgement. It can also reduce mechanical irritation at the insertion site.

Infusion pump safety check

Confirm the correct patient, solution or medication, concentration, programmed rate, line tracing, and alarm response. For high-alert infusions, follow the required independent-check process.

In-line filter: key rule

Use the filter specified by the medication, solution, manufacturer, or policy. A filter type is not universally interchangeable across infusates.

Closed-system transfer device (CSTD)

A CSTD is designed to limit the escape of hazardous drug vapor, aerosol, or liquid and to limit environmental contaminants entering the system. Use it as required by the hazardous-drug workflow.

Pediatric vascular access: planning principle

Plan early around therapy needs, developmental considerations, vein preservation, and family involvement. Repeated failed attempts can quickly exhaust limited access options.

Chronic kidney disease and vein preservation

Protect upper-extremity veins that may be needed for future dialysis access. Coordinate device decisions with the patient’s renal and vascular-access plan.

Infiltration versus extravasation

Infiltration is leakage of a nonvesicant into tissue. Extravasation is leakage of a vesicant, which can cause tissue injury. Both require immediate assessment and action.

Suspected vesicant extravasation: first action

Stop the infusion immediately. Do not flush; keep the device in place initially for aspiration or antidote steps as directed by the drug-specific protocol, then escalate promptly.

Occluded catheter: unsafe response

Never force a flush against resistance. Stop, assess for mechanical causes and complications, and follow the approved occlusion-management protocol.

Opioid infusion: high-priority assessment

Monitor pain relief together with sedation level and respiratory status. Increasing sedation or respiratory depression requires immediate action under the organization’s protocol.

Patient-controlled analgesia (PCA): safety principle

Only the patient should activate the demand button. Family- or staff-activated dosing can bypass the patient’s protective response to sedation.

Vasoactive infusion: monitoring principle

Give through the prescribed route with a controlled delivery device and closely monitor hemodynamic response. Titrate only under the ordered parameters and facility protocol.

Hazardous antineoplastic drugs: exposure control

Use the required PPE, engineering controls, and disposal process. Exposure prevention protects the patient, staff, and environment.

Why is antineoplastic extravasation urgent?

Some antineoplastic agents can cause severe local tissue injury. Stop the infusion, avoid flushing, preserve the device for protocol-directed aspiration or antidote steps, and escalate immediately.

Biologic infusion reaction: first priority

Recognize new symptoms promptly, stop or slow the infusion according to the ordered reaction protocol, assess airway and circulation, and notify the appropriate clinician.

Why monitor during a biologic infusion?

Infusion reactions may emerge during administration. Baseline assessment, ordered vital-sign checks, and patient education about reportable symptoms support early recognition.

Anti-infective infusion: pre-infusion check

Verify the patient, drug, dose, allergies, compatibility, route, and prescribed infusion rate. These checks help prevent avoidable medication and reaction errors.

Rate-related infusion reaction

A reaction can be caused or worsened by a rapid infusion rate. Assess the patient, pause or adjust the infusion only as the protocol or order directs, and escalate symptoms promptly.

Blood product administration: essential bedside check

Use the required patient-identification and product-verification process at the bedside before starting the transfusion. Identification errors can be catastrophic.

Suspected acute transfusion reaction

Stop the blood product, maintain IV access with the compatible solution specified by policy, assess the patient, and notify the provider and blood bank immediately.

Isotonic solution: clinical effect

An isotonic solution has osmolality similar to plasma and primarily expands the extracellular fluid compartment. Choose fluids based on the clinical indication and order.

Fluid volume excess: common clues

Watch for edema, weight gain, rising blood pressure, dyspnea, or crackles. Compare findings with the patient’s baseline and escalate clinically significant changes.

Potassium chloride IV safety

Never administer potassium chloride by IV push. Use the prescribed dilution, controlled rate, monitoring, and pump safeguards.

Medication compatibility check

Do not assume two IV medications are compatible because both are commonly used. Check current compatibility information for the specific concentrations, diluents, and administration method.

Parenteral nutrition (PN): metabolic monitoring

PN can affect glucose, electrolytes, triglycerides, liver function, and fluid balance. Monitor the ordered laboratory values and clinical response.

Why can central access be needed for PN?

Highly hyperosmolar PN formulations may require central venous administration to reduce the risk of peripheral vein injury. Match the formulation and route to the prescribed plan.

PN interruption: why is it a safety issue?

Abrupt interruption can create metabolic risk, especially with dextrose-containing PN. Follow the prescribed contingency plan and notify the appropriate clinician rather than improvising a substitute.

Infusion adverse reaction: first nursing priorities

Stop or pause the infusion as the protocol directs, assess airway, breathing, circulation, and symptoms, maintain access as appropriate, and escalate without delay.

Frequently Asked Questions

What does the CRNI® exam cover?

INCC organizes the scored exam into Principles of Practice (35 items), Access Devices (39), and Infusion Therapies (46).

How many CRNI® exam questions are there?

The exam presents 140 four-option multiple-choice items in 150 minutes. INCC scores 120 items; 20 unscored pretest items are mixed in.

What is the CRNI® passing score?

INCC reports a passing scaled score of 70. The required raw score can vary by form because INCC uses Angoff standard setting and pre-equating.

Who is eligible for the CRNI® exam?

Applicants need a current, active, unrestricted RN license and 1,600 hours of infusion-therapy experience as an RN within the prior two years. Qualifying work may include education, administration, research, or clinical practice.

How soon can I retake the CRNI® exam?

INCC publishes March and September testing windows and a $50 discount for previously unsuccessful candidates, but does not publish a fixed retake waiting interval or a separate rule after three failures.