A serum specimen is visibly hemolyzed. Which analyte is most likely to be falsely increased because of release from red blood cells?
Clinical Chemistry
Question · Easy
The ROME trick for blood gases
Short
Which additive is most appropriate when a blood glucose specimen cannot be separated from cells promptly and glycolysis must be inhibited?
Renal panel value that measures a protein-breakdown waste filtered by healthy kidneys.
Clinical chemistry
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Chapter 1: Clinical Chemistry: Laboratory Operations, Instrumentation, Reagents, Quality Assurance, and Safety
1.1 Specimen Collection, Preanalytical Variables, and Interferences
Study guide
A chemistry control result exceeds the laboratory's defined rejection rule. What should the technologist do before reporting patient results from that run?
Read the clue and guess the term in 6 tries.
Game
Which enzyme is more liver-specific and is commonly interpreted with AST when evaluating hepatocellular injury?
Liver enzyme used mainly to diagnose and monitor disease of the bile ducts and gallbladder, and a sensitive marker of hidden alcohol use.
Hemoglobin A1c is most useful because it reflects which clinical information?
Which handling step is most important for an arterial blood gas specimen?
Cholesterol carrier nicknamed 'good' cholesterol.
1.2 Clinical Chemistry Instrumentation, Photometry, and Automation
A creatinine result by the Jaffe reaction is unexpectedly high in a patient with marked ketonemia. What is the most likely analytical issue?
Question · Medium
Swap tiles to line up three of the same term.
Term Match
Which formula correctly calculates the serum anion gap using sodium, chloride, and bicarbonate?
Acute-phase marker measured directly in serum, unlike the sedimentation rate, that rises and falls quickly with acute inflammation or tissue destruction.
In Westgard multirule quality control, what does a 1-3s rule violation usually indicate?
A patient with severe hyperlipidemia has a low sodium result by an indirect ion-selective electrode method, but direct ISE sodium is normal. What best explains this discrepancy?
Routine panel that measures hemoglobin and platelets and estimates red cell volume.
Hematology
1.3 Quality Control, Westgard Rules, Calibration, and Laboratory Mathematics
Which cardiac marker is most specific and remains useful for detecting myocardial injury after CK-MB has begun to normalize?
Flip two cards at a time to find matching terms.
Term Pairs
A calibration is performed on a chemistry analyzer. What is the primary purpose of calibration?
Purple-top tube additive that forms calcium salts and removes calcium, preventing coagulation.
A delta check flags a patient's sodium result because it differs greatly from yesterday's value. What is the best first interpretation of the flag?
A patient has low total calcium and very low albumin, but ionized calcium is normal. What is the best explanation?
Blood index that measures the average size of erythrocytes.
1.4 Reagent Preparation, Laboratory Water, Glassware, Pipettes, and Centrifuges
Why should reference intervals be verified when a laboratory changes to a new method or analyzer?
Find five hidden terms in a grid of letters.
Term Search
A reagent blank is used in a colorimetric assay. What does it primarily correct for?
Calculated clotting value used most often to check how well warfarin is working and to guide dose changes.
An arterial blood gas shows pH 7.28, pCO2 60 mm Hg, and bicarbonate 27 mmol/L. Which interpretation best fits the primary disorder?
Question · Hard
A patient has high measured serum osmolality with a much lower calculated osmolality. Which finding does this osmolal gap most strongly suggest?
Blood group system with four major types; typing mixes blood with antibodies against two of its marker substances.
Blood banking and serology
1.5 Laboratory Safety: Chemical, Fire, Electrical, Biological, and Physical Hazards
A patient has markedly increased alkaline phosphatase with normal gamma-glutamyl transferase. Which source is most consistent with this pattern?
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A method comparison shows the new glucose method consistently reads 8 mg/dL higher than the comparison method across the reportable range. What type of error is suggested?
Blood bank procedure that detects antibodies already attached to red cells, rather than free antibodies in the serum.
In a Gram stain, bacteria that retain crystal violet after decolorization appear what color?
Microbiology Parasitology
Acid-fast staining is especially useful for organisms with which structural feature?
___ typing, also called tissue typing: blood test of cell-surface proteins used to find good matches for grafts and organ transplants.
Chapter 2: Clinical Chemistry: Carbohydrates, Lipids, Proteins, Non-Protein Nitrogen, and Liver Function
2.1 Glucose Homeostasis, Diagnostic Criteria for Diabetes Mellitus, and Glycemic Monitoring
Chocolate agar supports growth of Haemophilus influenzae because heating blood releases which growth factors?
Which direct microscopic preparation is commonly used to rapidly screen skin scrapings for fungal elements?
Nontreponemal syphilis assay whose titers frequently run slightly higher than VDRL titers.
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