1.1 Medical Terminology

Key Takeaways

  • Medical terms follow a consistent structure: prefix + root word + combining vowel + suffix, enabling interpretation of unfamiliar clinical terms
  • Common prefixes include hyper- (excessive), hypo- (deficient), tachy- (fast), brady- (slow), poly- (many), and dys- (difficult/painful)
  • Root words identify the body part: cardi/o (heart), pulmon/o (lung), gastr/o (stomach), hepat/o (liver), nephr/o (kidney), oste/o (bone)
  • Common suffixes indicate conditions or procedures: -itis (inflammation), -ectomy (surgical removal), -osis (abnormal condition), -algia (pain)
  • The combining vowel (usually "o") connects root words to suffixes beginning with consonants but is dropped before vowel-starting suffixes
  • Abbreviations like PRN (as needed), STAT (immediately), NPO (nothing by mouth), and BID (twice daily) are used daily in clinical settings
Last updated: March 2026

Medical Terminology

Medical terminology is the standardized language used throughout healthcare. Understanding how medical terms are constructed allows you to decode unfamiliar words, accurately document patient information, and communicate effectively with physicians, nurses, and other healthcare professionals.


Word Building: The Four Components

Every medical term is built from up to four components:

ComponentPositionFunctionExample
PrefixBeginningModifies meaninghyper- (excessive)
Root wordMiddle/coreIdentifies body part or conditioncardi (heart)
Combining vowelBetween root and suffixConnects components (usually "o")cardi/o/myopathy
SuffixEndIndicates procedure, condition, or disease-itis (inflammation)

Rules for combining vowels:

  • Use the combining vowel when the suffix starts with a consonant: cardi/o/logy
  • Drop the combining vowel when the suffix starts with a vowel: cardi/itis (not cardi/o/itis)
  • Always use the combining vowel between two root words: gastr/o/enter/itis

Essential Prefixes

PrefixMeaningExampleDefinition
a-, an-Without, absence ofApneaWithout breathing
hyper-Above, excessiveHypertensionHigh blood pressure
hypo-Below, deficientHypoglycemiaLow blood sugar
tachy-Fast, rapidTachycardiaFast heart rate (>100 bpm)
brady-SlowBradycardiaSlow heart rate (<60 bpm)
poly-Many, excessivePolyuriaExcessive urination
oligo-Few, scantyOliguriaDecreased urine output
dys-Difficult, painfulDyspneaDifficult breathing
anti-AgainstAntibioticAgainst bacteria
hemi-HalfHemiplegiaParalysis of one side
peri-AroundPericardiumMembrane around the heart
sub-Below, underSubcutaneousUnder the skin
supra-AboveSuprapubicAbove the pubic bone
inter-BetweenIntercostalBetween the ribs
intra-WithinIntravenousWithin a vein
post-AfterPostoperativeAfter surgery
pre-BeforePrenatalBefore birth
endo-WithinEndoscopyLooking within
epi-Upon, aboveEpigastricUpon the stomach region
retro-Behind, backwardRetroperitonealBehind the peritoneum

Essential Root Words

RootMeaningExample
cardi/oHeartCardiology
pulmon/oLungPulmonary
gastr/oStomachGastritis
hepat/oLiverHepatitis
nephr/o, ren/oKidneyNephrology, renal
oste/oBoneOsteoporosis
neur/oNerveNeurology
derm/o, dermat/oSkinDermatology
hem/o, hemat/oBloodHematology
arthr/oJointArthritis
my/oMuscleMyocardial
cyst/oBladderCystitis
encephal/oBrainEncephalitis
enter/oIntestineEnteritis
pneum/oLung, airPneumonia
col/oColonColitis
cyt/oCellCytology
lith/oStoneLithotripsy
path/oDiseasePathology
thromb/oClotThrombosis

Essential Suffixes

SuffixMeaningExample
-itisInflammationAppendicitis
-ectomySurgical removalAppendectomy
-otomyCutting intoTracheotomy
-ostomyCreating a new openingColostomy
-osisAbnormal conditionCyanosis
-ologyStudy ofCardiology
-algiaPainNeuralgia
-emiaBlood conditionAnemia
-pathyDiseaseNeuropathy
-scopeInstrument for viewingStethoscope
-scopyProcess of viewingEndoscopy
-plastySurgical repairRhinoplasty
-megalyEnlargementCardiomegaly
-peniaDeficiencyThrombocytopenia
-rrhage, -rrhagiaExcessive flow/bleedingHemorrhage
-rrhaphySuturingHerniorrhaphy
-rrheaFlow, dischargeDiarrhea
-centesisSurgical puncture to aspirateThoracentesis
-graphyProcess of recordingRadiography
-gramRecord or imageElectrocardiogram

Common Medical Abbreviations for CCMAs

Medical assistants must know these abbreviations used in clinical orders, documentation, and communication:

Frequency Abbreviations

AbbreviationMeaning
PRNAs needed (pro re nata)
STATImmediately
BIDTwice daily (bis in die)
TIDThree times daily (ter in die)
QIDFour times daily (quater in die)
QDEvery day (quaque die)
QODEvery other day
ACBefore meals (ante cibum)
PCAfter meals (post cibum)
HSAt bedtime (hora somni)

Route Abbreviations

AbbreviationMeaning
POBy mouth (per os)
IMIntramuscular
IVIntravenous
SubQ / SQSubcutaneous
IDIntradermal
SLSublingual (under the tongue)
PRPer rectum
TOPTopical

Clinical Abbreviations

AbbreviationMeaning
NPONothing by mouth (nil per os)
VSVital signs
BPBlood pressure
HRHeart rate
RRRespiratory rate
TTemperature
HtHeight
WtWeight
BMIBody mass index
SOBShortness of breath
CCChief complaint
HPIHistory of present illness
PMHPast medical history
ROSReview of systems
DxDiagnosis
TxTreatment
RxPrescription
HxHistory
SxSymptoms
NKA / NKDANo known allergies / No known drug allergies
UAUrinalysis
CBCComplete blood count
BMP / CMPBasic / Comprehensive metabolic panel
Hgb / HbHemoglobin
HctHematocrit
WBCWhite blood cell count
FBS / FBGFasting blood sugar / Fasting blood glucose

Do Not Use Abbreviations (Joint Commission)

The Joint Commission maintains a "Do Not Use" list of abbreviations that are prone to misinterpretation:

Do NOT UseProblemUse Instead
U (for units)Mistaken for "0" or "4"Write "units"
IU (international units)Mistaken for "IV"Write "international units"
Q.D. / Q.O.D.Mistaken for each otherWrite "daily" / "every other day"
MS / MSO4 / MgSO4MS confused with morphine/magnesiumWrite "morphine sulfate" or "magnesium sulfate"
Trailing zero (e.g., 1.0 mg)Decimal point missed → 10 mgWrite "1 mg"
Lack of leading zero (e.g., .5 mg)Decimal point missed → 5 mgWrite "0.5 mg"
Test Your Knowledge

The medical term "tachycardia" is built from which components?

A
B
C
D
Test Your Knowledge

What does the abbreviation "NPO" mean?

A
B
C
D
Test Your Knowledge

According to the Joint Commission "Do Not Use" list, which abbreviation should NOT be used in medical documentation?

A
B
C
D
Test Your KnowledgeFill in the Blank

The suffix "-ectomy" means surgical _____ of an organ or structure.

Type your answer below