Key Takeaways

  • Inflammation has five cardinal signs: redness (rubor), heat (calor), swelling (tumor), pain (dolor), and loss of function (functio laesa)
  • Acute inflammation is a short-term healing response; chronic inflammation persists beyond normal healing time and may cause tissue damage
  • Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain, fatigue, and tender points — massage should be gentle and within client tolerance
  • Osteoarthritis involves degeneration of articular cartilage; rheumatoid arthritis is an autoimmune disease attacking synovial membranes
  • Massage therapists must refer clients to a physician when encountering signs of undiagnosed conditions, infections, or conditions outside scope of practice
  • Red flags requiring immediate referral include unexplained weight loss, constant night pain, bowel/bladder dysfunction, and signs of stroke (FAST)
  • Trigger points are hyperirritable spots in taut bands of muscle that refer pain to predictable patterns
  • Tendinitis is inflammation of a tendon; tendinosis is chronic tendon degeneration without significant inflammation
Last updated: February 2026

Common Pathologies & Referral Guidelines

Massage therapists work with clients who have a wide range of health conditions. Understanding common pathologies, their signs and symptoms, and when to refer to a physician is essential for safe, effective practice.


The Inflammatory Process

Inflammation is the body's natural response to tissue injury, infection, or irritation. The five cardinal signs of inflammation are:

SignLatin TermDescription
RednessRuborIncreased blood flow to the area
HeatCalorWarmth from increased blood flow and metabolic activity
SwellingTumorFluid accumulation (edema) in the tissues
PainDolorIrritation of nerve endings by chemical mediators
Loss of functionFunctio laesaReduced ability to use the affected area

Acute vs. Chronic Inflammation

FeatureAcute InflammationChronic Inflammation
DurationHours to daysWeeks, months, or years
PurposeProtective healing responsePersistent, often damaging
SignsClassic five cardinal signsMay have subtle or systemic signs
TreatmentRest, ice, elevation, medical careMultidisciplinary approach
MassageGenerally contraindicated locally during acute phaseMay be beneficial with appropriate techniques

Common Musculoskeletal Conditions

Fibromyalgia

  • Definition: Chronic condition characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and cognitive difficulties ("fibro fog")
  • Key features: Pain in multiple body regions for 3+ months; tender points; associated with depression and anxiety
  • Massage considerations: Use gentle, moderate-pressure techniques within client tolerance. Avoid deep tissue work on flare-up days. Massage can help reduce pain and improve sleep quality.

Osteoarthritis (OA)

  • Definition: Degenerative joint disease — articular cartilage wears down over time
  • Key features: Joint pain and stiffness (worse with activity, better with rest), crepitus, reduced ROM, Heberden's nodes (DIP joints) and Bouchard's nodes (PIP joints)
  • Massage considerations: Avoid direct pressure on acutely inflamed joints. Gentle ROM exercises and massage around the joint can improve circulation and reduce stiffness.

Rheumatoid Arthritis (RA)

  • Definition: Autoimmune disease that attacks the synovial membranes of joints
  • Key features: Bilateral/symmetrical joint involvement, morning stiffness lasting >30 minutes, joint deformity over time, systemic symptoms (fatigue, fever)
  • Massage considerations: Avoid massage during acute flare-ups. During remission, gentle massage may help. Always obtain physician clearance.

Tendinitis vs. Tendinosis

FeatureTendinitisTendinosis
DefinitionAcute inflammation of a tendonChronic degeneration of tendon tissue
DurationShort-term (days to weeks)Long-term (months to years)
InflammationPresentMinimal or absent
Pain patternAcute, sharp with movementChronic, dull ache
TreatmentRest, ice, anti-inflammatoriesEccentric exercises, friction massage, gradual loading
MassageAvoid during acute phase; gentle work afterCross-fiber friction may be beneficial

Trigger Points

  • Definition: Hyperirritable spots within taut bands of skeletal muscle that produce local and referred pain
  • Types: Active (cause spontaneous pain and referral patterns) and latent (only painful when pressed)
  • Treatment: Ischemic compression, trigger point release, positional release, stretching
  • Key referral patterns:
    • Upper trapezius → temporal headache (side of head)
    • SCM (sternocleidomastoid) → frontal headache, dizziness, visual disturbances
    • Infraspinatus → anterior shoulder and arm pain
    • Piriformis → buttock and posterior thigh pain (mimics sciatica)
    • Levator scapulae → angle of the neck, medial scapular border
    • Gluteus minimus → lateral thigh and leg pain (mimics sciatica)
    • Subscapularis → posterior shoulder and wrist pain
    • Soleus → heel and plantar foot pain

Healing Process Phases

Understanding the stages of tissue healing guides massage treatment decisions:

PhaseTimelineWhat HappensMassage Approach
Inflammatory0-5 daysRedness, heat, swelling, pain; clot formation; debris removalAvoid the area; RICE protocol; lymphatic drainage above the injury
Proliferative3 days - 3 weeksNew tissue formation; collagen laid down (disorganized); granulation tissueVery light work around the area; encourage gentle movement
Remodeling3 weeks - 2+ yearsCollagen reorganizes along stress lines; tissue strengthensCross-fiber friction, stretching, progressive pressure to remodel scar tissue

Common Skin Conditions

ConditionTypeContagious?Massage Consideration
Ringworm (tinea)FungalYes — highly contagiousLocal contraindication — no massage on or near the lesion
ImpetigoBacterialYesLocal contraindication — avoid the area
WartsViral (HPV)Yes — contact transmissionLocal contraindication — avoid the wart
Herpes simplexViralYes — during active outbreakLocal contraindication during active outbreak
PsoriasisAutoimmuneNoMay massage with client comfort; avoid over plaques if irritated
Eczema (dermatitis)InflammatoryNoMay massage with gentle, hypoallergenic products; avoid flared areas
AcneBacterial/hormonalNoAvoid inflamed areas; light touch on affected regions
MelanomaCancerNoDo NOT massage; refer to physician immediately

When to Refer to a Physician

Red Flags Requiring Immediate Referral

Massage therapists must refer clients to a physician when they identify:

  • Unexplained weight loss (>10% body weight without trying)
  • Constant pain at night that is not relieved by position changes
  • Bowel or bladder dysfunction (possible cauda equina syndrome)
  • Signs of stroke (FAST): Face drooping, Arm weakness, Speech difficulty, Time to call 911
  • Signs of DVT (deep vein thrombosis): Unilateral leg swelling, redness, warmth, and calf pain
  • Unexplained lumps or masses
  • Signs of infection: Fever, red streaks, pus, rapidly spreading redness
  • Severe headache described as "the worst headache of my life"
  • Numbness or tingling that is progressive or accompanied by weakness
  • Recent unexplained bruising or bleeding abnormalities

Additional Common Conditions

Carpal Tunnel Syndrome

  • Definition: Compression of the median nerve as it passes through the carpal tunnel at the wrist
  • Symptoms: Numbness, tingling, and pain in the thumb, index, middle, and half of the ring finger; weakness in grip
  • Massage considerations: Massage of the forearm flexors and gentle wrist mobilization may help; avoid direct deep pressure over the carpal tunnel; refer for medical evaluation
  • Common in: Office workers, massage therapists, anyone with repetitive wrist motions

Thoracic Outlet Syndrome (TOS)

  • Definition: Compression of nerves and/or blood vessels between the clavicle and first rib
  • Symptoms: Pain, numbness, and tingling in the arm and hand; may be vascular (swelling, discoloration) or neurogenic (more common)
  • Massage considerations: Release tight scalenes, pectoralis minor, and SCM; improve posture; avoid positions that reproduce symptoms

Sciatica

  • Definition: Pain radiating along the sciatic nerve (lower back through the buttock and down the leg)
  • Causes: Herniated disc, piriformis syndrome, spinal stenosis, degenerative disc disease
  • Massage considerations: Address piriformis and gluteal muscles; avoid deep pressure on the lumbar spine if disc involvement is suspected; refer for medical evaluation if symptoms are severe or progressive

Plantar Fasciitis

  • Definition: Inflammation and degeneration of the plantar fascia on the bottom of the foot
  • Symptoms: Sharp heel pain, especially with first steps in the morning
  • Massage considerations: Deep friction massage of the plantar fascia, stretching of the gastrocnemius and soleus, cross-fiber friction at the calcaneal attachment

Temporomandibular Joint Dysfunction (TMJ/TMD)

  • Definition: Pain and dysfunction of the temporomandibular joint and associated muscles
  • Symptoms: Jaw pain, clicking/popping, difficulty opening the mouth, headaches, ear pain
  • Massage considerations: Gentle massage of the masseter, temporalis, medial and lateral pterygoids (intraoral work requires special training and consent); address SCM and suboccipital muscles
Test Your Knowledge

What are the five cardinal signs of inflammation?

A
B
C
D
Test Your Knowledge

A client presents with bilateral joint swelling, morning stiffness lasting over an hour, and fatigue. This is most consistent with:

A
B
C
D
Test Your Knowledge

A massage therapist discovers an unexplained lump during a session. The appropriate action is to:

A
B
C
D
Test Your Knowledge

Cross-fiber friction massage is most appropriate for which condition?

A
B
C
D
Test Your KnowledgeMulti-Select

Which of the following are RED FLAGS that require immediate physician referral? (Select all that apply)

Select all that apply

Unexplained weight loss of >10% body weight
Mild muscle soreness after exercise
Constant night pain not relieved by position change
Occasional tension headache
Signs of deep vein thrombosis (unilateral leg swelling, warmth)
Delayed onset muscle soreness (DOMS)
Test Your KnowledgeFill in the Blank

Trigger points in the upper trapezius muscle commonly refer pain in a ___ headache pattern.

Type your answer below

Test Your Knowledge

Carpal tunnel syndrome involves compression of which nerve?

A
B
C
D
Test Your Knowledge

Which condition is characterized by chronic tendon degeneration WITHOUT significant inflammation?

A
B
C
D
Test Your KnowledgeOrdering

Arrange the stages of tissue healing in the correct chronological order.

Arrange the items in the correct order

1
Remodeling/Maturation phase (months to years)
2
Inflammatory phase (0-5 days)
3
Proliferative/Repair phase (3 days - 3 weeks)