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Cheat sheet

CGRN Cheat Sheet

General Nursing Care

21%of exam

GI AnatomyGI ConditionsAssessmentPharmacologyPatient Rights

GI Procedures

35%of exam

Endoscopic ProceduresScope AnatomyAccessoriesSedationSpecimen Handling

Patient Care Interventions

25%of exam

ComplicationsResuscitationGI BleedingMedicationsIV + Nutrition

Safety + Infection Control

19%of exam

ReprocessingDisinfection LevelsPPEMDRO + C. diffChemical Safety

Quick Facts

Exam
CGRN
Body
ABCGN / Prometric
Questions
175 (150 scored)
Time
3 hours
Pass
450 scaled score
Valid
5 years
Fee
$430-$520
Blueprint
ABCGN 2026

Crohn's vs Ulcerative Colitis

Crohn's

  • Transmural
  • Skip lesions
  • Mouth to anus

UC

  • Mucosa only
  • Continuous
  • Colon/rectum

Patchy depth vs continuous mucosa

GI Anatomy

LES
Esophagus-stomach sphincter
Pylorus
Stomach-duodenum valve
Duodenum
First small intestine
Ampulla of Vater
Bile/pancreatic duct outlet
Sphincter of Oddi
Controls ampulla flow
Ileocecal valve
Ileum-to-colon junction
Bile
Emulsifies dietary fat

GI Conditions

GERD
Acid reflux esophagitis
Barrett's
Precancerous esophageal metaplasia
PUD
Gastric/duodenal ulcer
Ulcerative colitis
Continuous colonic mucosa
Crohn's
Transmural, skip lesions
Cirrhosis
Liver scarring, varices
Pancreatitis
Elevated lipase/amylase
Dysphagia + weight loss
Red-flag malignancy

Assessment

Allergy check
Latex, contrast, drugs
Anticoagulants
Bleeding risk review
NPO status
Confirm aspiration risk
Baseline vitals
Pre-sedation reference
ASA class
Sedation risk stratifier
Time-out
Verify patient/procedure

GI Pharmacology

PPI
Blocks acid pump
H2 blocker
Reduces gastric acid
Simethicone
Reduces bowel gas
PEG solution
Colonoscopy bowel prep
5-ASA
IBD anti-inflammatory
Octreotide
Reduces splanchnic flow

Professional Issues

HIPAA
Protects patient privacy
Informed consent
Provider obtains; nurse witnesses
Scope of practice
State/role limits
Advance directive
Patient care wishes
Documentation
Objective, timely, accurate
Patient advocacy
Protect patient interests

Moderate vs Deep Sedation

Moderate

  • Purposeful response
  • Airway maintained
  • RN may monitor

Deep

  • Repeated stimulus
  • Airway risk
  • Anesthesia provider

Responsive vs anesthesia-led

Sedation Level Picker

  1. Routine EGD/colonoscopyModerate sedation(Midazolam + fentanyl)
  2. Anxiety/anxiolysis onlyMinimal sedation(Responds normally)
  3. Long/complex ERCPDeep sedation(Anesthesia-administered)
  4. Propofol orderedAnesthesia provider(Not RN-pushed)
  5. High ASA/airway riskAnesthesia consult(Plan escalation)
  6. Patient unarousableStop + support airway(Oversedation)

Endoscopic Procedures

EGD
Upper GI scope
Colonoscopy
Full colon exam
ERCP
Biliary/pancreatic duct access
EUS
Ultrasound staging/sampling
Sigmoidoscopy
Distal colon only
Capsule endoscopy
Small-bowel imaging
Polypectomy
Removes colon polyp
Variceal banding
Ligates esophageal varices

EGD vs Colonoscopy

EGD

  • Upper GI tract
  • NPO prep
  • Bite block

Colonoscopy

  • Colon
  • Bowel prep
  • Left lateral

Upper scope vs lower scope

Scope + Accessories

Insertion tube
Flexible scope shaft
Air/water channel
Insufflation + lens rinse
Biopsy channel
Suction + accessories
Elevator
Duodenoscope accessory guide
Biopsy forceps
Obtains tissue sample
Snare
Polyp resection loop
Cytology brush
Cellular sampling tool
Hemoclip
Mechanical bleeding control

EGD Path

Step 1
Mouth + oropharynx
Step 2
Esophagus
Step 3
Stomach
Step 4
Pylorus
Step 5
Duodenum
Bite block
Protects scope/teeth

Specimen Handling

Formalin
Routine histology fixative
Saline
H. pylori rapid test
Label at bedside
Two patient identifiers
Site labeling
Document biopsy location
Cytology
Brushings/fluid analysis
Chain of custody
Tracked specimen handoff

Sedation Agents

Midazolam
Benzodiazepine, amnesia/anxiolysis
Fentanyl
Opioid analgesia
Propofol
Deep sedation, anesthesia-led
Flumazenil
Reverses benzodiazepine
Naloxone
Reverses opioid
Topical anesthetic
Suppresses gag reflex
Capnography
Monitors exhaled CO2

Perforation Triad

Pain + Fever + Leukocytosis = perforation

Severe painFeverRising WBCNotify provider

Flumazenil vs Naloxone

Flumazenil

  • Reverses benzodiazepine
  • Midazolam antidote
  • Seizure caution

Naloxone

  • Reverses opioid
  • Fentanyl antidote
  • Re-sedation watch

Benzo reversal vs opioid reversal

Complication Response Picker

  1. Pain, fever, leukocytosisSuspect perforation(Notify provider, NPO)
  2. Hypoxia post-sedationAirway + oxygen(Reversal if opioid/benzo)
  3. Delayed rectal bleedingPost-polypectomy bleed(Assess hemodynamics)
  4. Pain + lipase post-ERCPSuspect pancreatitis(Monitor, IV fluids)
  5. Bradycardia + hypotensionVasovagal response(Stop, position, fluids)
  6. Apneic + pulselessBegin CPR(Activate code)

Procedure Complications

Perforation
Pain, fever, leukocytosis
Post-polypectomy bleed
Delayed hematochezia
Post-ERCP pancreatitis
Pain, elevated lipase
Aspiration
Gastric contents, hypoxia
Oversedation
Hypoventilation, hypoxemia
Vasovagal
Bradycardia, hypotension
Cholangitis
Fever, jaundice, RUQ pain

Reversal Pairing

Flumazenil = benzo | Naloxone = opioid

Flumazenil: midazolamNaloxone: fentanylWatch re-sedation

Upper vs Lower GI Bleed

Upper

  • Hematemesis
  • Melena
  • Above ligament Treitz

Lower

  • Hematochezia
  • Bright red
  • Below ligament Treitz

Black/vomited vs bright rectal

Emergency Response

Unresponsive + apneic
Start CPR
Stop procedure
First with instability
Airway first
Reposition, oxygen, suction
Reversal agents
Naloxone/flumazenil ready
Crash cart
Defibrillator + emergency drugs
Trendelenburg
Hypotension positioning

GI Bleeding + Therapy

Hematemesis
Upper GI bleed
Melena
Upper GI bleed
Hematochezia
Lower GI bleed
Octreotide
Variceal bleed adjunct
Epinephrine injection
Endoscopic hemostasis
Large-bore IV
Rapid volume access

IV + Nutrition

Isotonic crystalloid
Initial volume replacement
NS / LR
First-line resuscitation fluids
Hypokalemia
Vomiting/diarrhea risk
Enteral nutrition
Gut works first
TPN
Nonfunctional GI tract
Refeeding risk
Monitor phosphate/potassium

Reprocessing Order

Preclean | Leak | Clean | HLD | Dry | Store

Preclean: bedsideLeak: detect damageHLD: disinfectDry: alcohol/air

HLD vs Sterilization

HLD

  • Semicritical items
  • Flexible endoscopes
  • Kills most microbes

Sterilization

  • Critical items
  • Biopsy forceps
  • Kills all spores

Contacts mucosa vs sterile tissue

Reprocessing Level Picker

  1. Flexible endoscopeHigh-level disinfection(Semicritical)
  2. Biopsy forcepsSterilization(Critical, breaks mucosa)
  3. Snare/cytology brushSterilize or single-use(Critical)
  4. BP cuff/stethoscopeLow-level disinfection(Noncritical)
  5. Visibly soiled scopeManual clean first(Before HLD)
  6. Reprocessing failedRepeat full cycle(Do not use)

Scope Reprocessing

Step 1: Precleaning
Bedside wipe, channel flush
Step 2: Leak test
Detect scope damage
Step 3: Manual clean
Brush + enzymatic detergent
Step 4: HLD
High-level disinfection
Step 5: Rinse/dry
Alcohol flush, forced air
Step 6: Storage
Hang vertical, ventilated

C. diff Hygiene

C. diff = soap and water, not gel

Spore-formingAlcohol failsContact precautions

Disinfection Levels

Critical item
Sterilization required
Semicritical item
High-level disinfection minimum
Noncritical item
Low-level disinfection
Flexible endoscope
Semicritical = HLD
Biopsy forceps
Critical = sterilize
Spaulding system
Classifies reprocessing level

Infection Control

C. difficile
Soap and water
Alcohol gel
Ineffective on spores
Contact precautions
Gown + gloves
MDRO
Multidrug-resistant organism
Standard precautions
All patients, all time
Single-use accessory
Do not reprocess

PPE + Chemical Safety

PPE
Gloves, gown, eye/face
Glutaraldehyde
Respiratory/skin irritant
OPA
Stains skin gray
SDS
Chemical hazard reference
Ventilation
Limits vapor exposure
Body mechanics
Prevents staff injury

Common Traps

HLD vs sterilize

Scope = HLD Forceps = sterilize

Wrong reversal agent

Flumazenil = benzo Naloxone = opioid

C. diff hand hygiene

Soap and water Not alcohol gel

Consent responsibility

Provider obtains Nurse witnesses only

Crohn's vs UC

Crohn's transmural skip UC continuous mucosa

Bleed location

Melena = upper Hematochezia = lower

RN propofol limit

Propofol = anesthesia Not RN-administered

Last Minute

  1. 1.Weights: 21 / 35 / 25 / 19
  2. 2.GI Procedures = largest domain
  3. 3.Scope = HLD; forceps = sterilize
  4. 4.Flumazenil = benzo; naloxone = opioid
  5. 5.C. diff = soap and water
  6. 6.Perforation = pain, fever, WBC
  7. 7.Provider obtains consent; nurse witnesses
  8. 8.Propofol = anesthesia provider only
  9. 9.Melena = upper; hematochezia = lower
  10. 10.Preclean before high-level disinfection
  11. 11.Unstable = stop procedure first