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100+ Free CCRA Practice Questions

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2026 Statistics

Key Facts: CCRA Exam

125

Total Questions

ACRP (100 scored + 25 pretest)

3 hours

Exam Time

ACRP Certification Handbook

600

Passing Scaled Score

ACRP scoring (200-800 scale)

$435–$600

Exam Fee

ACRP (varies by membership/timing)

~70%

First-Attempt Pass Rate

ACRP annual report data

3,000 hrs

Experience Required

ACRP eligibility criteria

ACRP's CCRA exam uses 125 total items (100 scored + 25 pretest), with a 3-hour time limit and a passing scaled score of 600 on a 200-800 scale. Fees range from $435 to $600 depending on ACRP membership and registration timing. Content spans six domains: Scientific Concepts (8%), Ethical/Safety (20%), Product Development/Regulation (10%), Clinical Trial Operations/GCPs (25%), Study/Site Management (25%), and Data Management (12%). The exam references ICH guidelines exclusively.

About the CCRA Exam

The ACRP CCRA certification validates proficiency in clinical trial monitoring and management. The exam covers ICH Good Clinical Practice guidelines, informed consent, adverse event reporting, site monitoring, investigational product accountability, and data management across global clinical research settings.

Questions

100 scored questions

Time Limit

3 hours

Passing Score

Scaled score 600

Exam Fee

$435–$600 (ACRP)

CCRA Exam Content Outline

8%

Scientific Concepts and Research Design

Protocol components, study design rationale, product development plans, and research methodology

20%

Ethical and Participant Safety Considerations

Informed consent, IRB/IEC oversight, adverse event reporting, safety monitoring, and participant rights

10%

Product Development and Regulation

Drug and device development lifecycle, regulatory submissions, and ICH guideline application

25%

Clinical Trial Operations (GCPs)

Delegation of responsibilities, protocol amendments, investigator oversight, SOPs, and audit readiness

25%

Study and Site Management

Site monitoring visits, investigational product management, communication, non-compliance, and vendor oversight

12%

Data Management and Informatics

Source data verification, CRF completion, data queries, database lock procedures, and electronic systems

How to Pass the CCRA Exam

What You Need to Know

  • Passing score: Scaled score 600
  • Exam length: 100 questions
  • Time limit: 3 hours
  • Exam fee: $435–$600

Keys to Passing

  • Complete 500+ practice questions
  • Score 80%+ consistently before scheduling
  • Focus on highest-weighted sections
  • Use our AI tutor for tough concepts

CCRA Study Tips from Top Performers

1Clinical Trial Operations + Study/Site Management together make 50% of the exam — prioritize these domains
2Know ICH E6(R2) GCP inside and out: it is the primary reference for all exam questions
3Master the monitoring visit lifecycle: pre-study, initiation, interim/routine, and close-out visits
4Practice informed consent scenarios including re-consent triggers and documentation requirements
5Study adverse event reporting timelines and the difference between AEs, SAEs, and SUSARs

Frequently Asked Questions

How many questions are on the CCRA exam?

The CCRA exam has 125 total multiple-choice questions: 100 scored items and 25 unscored pretest items. Pretest items are not identified to candidates and do not affect your score.

How long is the CCRA exam?

ACRP allows a maximum of 3 hours (180 minutes) to complete all 125 questions on the CCRA exam.

What score do I need to pass the CCRA exam?

You need a scaled score of 600 or higher on a 200-800 scale to pass the CCRA. Raw scores are converted to scaled scores using psychometric methods; the exam is not scored on a curve.

How much does the CCRA exam cost?

Total fees range from $435 to $600 depending on ACRP membership status and early-bird vs. regular registration. ACRP members with early-bird registration pay $435; non-members at regular registration pay up to $600.

What experience do I need for CCRA eligibility?

ACRP requires 3,000 hours of verifiable work experience in human subject research. There is no specific degree requirement. Experience must be paid, contractual, and verifiable by your employer.

How should I prepare for the CCRA exam in 2026?

Focus on the two largest domains: Clinical Trial Operations and Study/Site Management (25% each, 50% total). Study the ICH E6(R2) guidelines thoroughly and note that E6(R3) replaces E6(R2) starting July 15, 2026. Practice scenario-based questions on monitoring visits, informed consent, and adverse event reporting.