A G1P0 patient at 36 weeks of gestation presents with a 3-day history of nausea, vomiting, epigastric pain, and progressive jaundice. Laboratory evaluation reveals: AST 350 U/L, ALT 380 U/L, total bilirubin 6.2 mg/dL, platelets 85,000/microL, fibrinogen 150 mg/dL, glucose 48 mg/dL, and elevated serum ammonia. What is the most likely diagnosis, and what is the immediate treatment?
- AHELLP syndrome; administer corticosteroids and delay delivery for 48 hours
- BAcute fatty liver of pregnancy (AFLP); stabilize maternal status (including correcting hy…
- CIntrahepatic cholestasis of pregnancy (ICP); prescribe ursodeoxycholic acid and deliver a…
- DViral hepatitis A; provide supportive care and avoid delivery until resolution