On continuous EEG monitoring, a pattern of generalized periodic discharges (GPDs) at 1 Hz is present. Over the next 2 hours, the frequency gradually increases to 2.5 Hz with superimposed rhythmic activity, and the patient develops subtle facial twitching. Per ACNS criteria, the transition from GPDs to electrographic seizure activity is BEST defined by:
- AAny increase in GPD frequency above 1.5 Hz
- BDefinite evolution in frequency, morphology, or spatial distribution, or presence of >2.5…
- CPresence of any motor manifestation
- DDuration exceeding 30 minutes