During the transition from the cap stage to the bell stage of tooth development, which transient non-dividing epithelial cell cluster serves as the primary organizational signaling center of the tooth germ, orchestrating crown shape and cusp morphogenesis via secretion of morphogens (BMP-2/4, FGF-4, Wnt-10b, and Shh)?
- AThe primary enamel knot (nœud de l'émail primaire)
- BThe dental follicle (sac folliculaire)
- CThe epithelial rests of Serres
- DThe stratum intermedium