Key Takeaways

  • Mechanical ventilation accounts for approximately 30% of the TMC exam — prioritize this content area
  • Focus on clinical application and decision-making rather than rote memorization of facts
  • The Interventions domain (50%) is the largest content area and should receive the most study time
  • Practice interpreting ABGs quickly — this is one of the most frequently tested topics
  • Use the "most appropriate" and "best next step" frameworks when answering clinical questions
  • Study in blocks matching exam timing: 160 questions in 3 hours = about 1 minute 7 seconds per question
  • Create clinical decision flowcharts for ventilator management, ABG interpretation, and emergency protocols
Last updated: February 2026

Study Strategies for the TMC Exam

The TMC exam tests your ability to apply respiratory therapy knowledge in clinical scenarios. Success requires more than memorizing facts — you must demonstrate clinical reasoning, prioritization skills, and the ability to select the most appropriate intervention for each patient situation.

Time Management Strategy

With 160 questions in 3 hours, you have approximately 1 minute and 7 seconds per question. Here is how to manage your time effectively:

StrategyDetails
First passAnswer questions you know immediately (~45 seconds each)
Flag and move onMark difficult questions and return to them
Second passReview flagged questions with remaining time
Don't overthinkYour first instinct is often correct on clinical questions
Time checkpointsAt 1 hour: ~53 questions; at 2 hours: ~107 questions

High-Yield Content Areas

Based on the TMC content outline, focus your study time proportionally:

Top Priority (50% of exam — Interventions):

  • Mechanical ventilation modes, settings, and troubleshooting
  • Oxygen therapy devices and delivery calculations
  • Airway management (intubation, suctioning, tracheostomy care)
  • Pharmacology (bronchodilators, corticosteroids, mucolytics)
  • CPR/ACLS protocols

Second Priority (36% of exam — Patient Data Evaluation):

  • ABG interpretation (pH, PaCO2, PaO2, HCO3, SaO2)
  • Pulmonary function testing (FEV1, FVC, FEV1/FVC ratio)
  • Hemodynamic monitoring (CVP, PAP, PCWP)
  • Lab values and diagnostic data interpretation

Third Priority (14% of exam — Troubleshooting & Infection Control):

  • Ventilator alarm management
  • Equipment troubleshooting
  • Infection control precautions
  • VAP prevention bundles

ABG Interpretation — The Most Tested Topic

ABG interpretation appears across multiple content areas. Master this systematic approach:

  1. Check pH: Normal 7.35-7.45 (acidosis < 7.35, alkalosis > 7.45)
  2. Check PaCO2: Normal 35-45 mmHg (respiratory component)
  3. Check HCO3: Normal 22-26 mEq/L (metabolic component)
  4. Determine primary disorder: Which component matches the pH direction?
  5. Check for compensation: Is the other component trying to normalize pH?
  6. Assess oxygenation: PaO2 normal 80-100 mmHg on room air

Clinical Decision-Making Framework

For questions asking "What is the MOST appropriate action?" or "What should the RT do NEXT?":

  1. Assess the patient first — Is there an immediate life threat?
  2. Identify the underlying problem — What does the data tell you?
  3. Select the least invasive effective intervention — Start simple, escalate as needed
  4. Consider the clinical context — A COPD patient is managed differently from an asthma patient
  5. Evaluate the response — Did the intervention work? What is the next step?

Study Schedule Recommendation

WeekFocus AreaActivities
Weeks 1-2Patient Data EvaluationABGs, PFTs, hemodynamics, lab values
Weeks 3-5Mechanical VentilationModes, settings, waveforms, troubleshooting
Weeks 6-7Airway, O2, PharmacologyDevices, drugs, calculations
Weeks 8Infection Control & ReviewPrecautions, equipment, full practice exams
Test Your Knowledge

Approximately what percentage of the TMC exam covers mechanical ventilation?

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Test Your Knowledge

A patient has the following ABG results: pH 7.28, PaCO2 58 mmHg, HCO3 24 mEq/L, PaO2 62 mmHg. What is the interpretation?

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Test Your Knowledge

When answering TMC exam questions that ask "What should the RT do NEXT?", what is the correct approach?

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Test Your Knowledge

How much time per question should you budget on the TMC exam (160 questions in 3 hours)?

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Test Your KnowledgeMulti-Select

Which of the following are high-yield study topics that together make up the MAJORITY of TMC exam content? (Select all that apply)

Select all that apply

Mechanical ventilation modes and settings
ABG interpretation
History of respiratory therapy as a profession
Oxygen therapy devices and delivery
Respiratory pharmacology
Hospital billing and coding procedures