Key Takeaways

  • Four routes of poisoning exposure: ingestion, inhalation, injection, and absorption (skin/eyes)
  • Opioid overdose triad: pinpoint pupils (miosis), respiratory depression, and altered mental status
  • Naloxone (Narcan) dose: intranasal 4 mg or intramuscular 0.4-2 mg -- may need to repeat every 2-3 minutes
  • Carbon monoxide poisoning causes headache, nausea, confusion -- cherry red skin is a late/unreliable sign; SpO2 readings may be falsely normal
  • SLUDGEM mnemonic for organophosphate poisoning: Salivation, Lacrimation, Urination, Defecation, GI distress, Emesis, Miosis
  • Hypothermia classifications: mild (90-95 degrees F), moderate (82-90 degrees F), severe (<82 degrees F)
  • Heat stroke is a life-threatening emergency with altered mental status and core temp >104 degrees F -- requires aggressive cooling
  • Near-drowning: prioritize airway management and ventilation; do NOT attempt to drain water from lungs
Last updated: February 2026

Poisoning, Overdose & Environmental Emergencies

Poisoning, overdose, and environmental emergencies encompass a wide range of conditions. EMTs must be able to identify the type of exposure, recognize toxidromes (toxic syndromes), and provide appropriate treatment.

Routes of Poisoning Exposure

RouteExamplesEMT Considerations
IngestionMedications, household chemicals, plants, contaminated foodMost common route; do NOT induce vomiting
InhalationCarbon monoxide, smoke, chemical fumes, gasesEnsure scene safety; remove patient from environment
InjectionSnake/insect bites, IV drug use, needle sticksLook for injection sites; assess for envenomation
AbsorptionPesticides, chemical agents, poison ivy/oakRemove contaminated clothing; irrigate skin

General Poisoning Management

  1. Scene safety -- protect yourself from exposure
  2. Identify the substance if possible (bring container to hospital)
  3. Contact Poison Control Center: 1-800-222-1222
  4. Do NOT induce vomiting unless directed by Poison Control
  5. Manage ABCs and transport
  6. Bring all pill bottles, containers, or substances found at the scene

Opioid Overdose

The opioid epidemic has made this one of the most common overdose presentations EMTs encounter.

Common Opioids

  • Heroin, fentanyl, carfentanil
  • Prescription opioids: oxycodone, hydrocodone, morphine, methadone

Opioid Toxidrome (Classic Triad)

  • Pinpoint pupils (miosis)
  • Respiratory depression (slow, shallow, or absent breathing)
  • Altered mental status (unresponsive or severely decreased consciousness)

Naloxone (Narcan) Administration

Naloxone is an opioid antagonist that reverses the effects of opioids.

RouteDoseNotes
Intranasal (IN)4 mg (one spray in one nostril)Preferred prehospital route -- no needles
Intramuscular (IM)0.4-2 mgInject into deltoid or lateral thigh
Intravenous (IV)0.4-2 mgALS intervention

Key Points:

  • May repeat every 2-3 minutes if no response
  • Onset: IN ~3-5 minutes, IM ~3-5 minutes, IV ~2 minutes
  • Duration of naloxone (30-90 minutes) is shorter than most opioids -- patient may re-sedate
  • Provide BVM ventilation while waiting for naloxone to take effect
  • Patient may become agitated, combative, or experience withdrawal symptoms upon waking
  • Be prepared for vomiting -- have suction ready

Carbon Monoxide (CO) Poisoning

Carbon monoxide is an odorless, colorless gas that binds to hemoglobin with 200-250 times greater affinity than oxygen, forming carboxyhemoglobin (COHb).

Sources

  • Furnaces, water heaters, generators
  • House fires, car exhaust
  • Poorly ventilated spaces with combustion

Signs and Symptoms

  • Early: Headache, nausea, dizziness, fatigue (often mistaken for flu)
  • Progressive: Confusion, visual changes, chest pain, shortness of breath
  • Severe: Seizures, loss of consciousness, cardiac arrest
  • Cherry red skin -- classically taught but actually a late and unreliable sign
  • SpO2 may read falsely normal (pulse oximeter cannot distinguish COHb from O2Hb)

Treatment

  • Remove from exposure (ensure scene safety)
  • High-flow oxygen via NRB at 15 L/min -- this is the primary treatment
  • Half-life of COHb: ~4-6 hours on room air, ~60-90 minutes on 100% O2
  • Transport to facility with hyperbaric oxygen capability if severe

Organophosphate Poisoning

Organophosphates (found in pesticides and nerve agents) inhibit acetylcholinesterase, causing excessive acetylcholine accumulation.

SLUDGEM Mnemonic

LetterSign/Symptom
SSalivation (excessive drooling)
LLacrimation (tearing)
UUrination (involuntary)
DDefecation (involuntary)
GGI distress (cramping, nausea)
EEmesis (vomiting)
MMiosis (pinpoint pupils)

Additional Signs

  • Bradycardia
  • Bronchospasm and bronchorrhea (excessive secretions)
  • Muscle fasciculations (twitching)
  • Seizures

EMT Treatment

  • Decontaminate -- remove clothing, brush off dry chemicals, irrigate with water
  • Protect yourself -- wear appropriate PPE (gloves, gown at minimum)
  • Manage airway -- suction copious secretions
  • High-flow oxygen
  • Transport rapidly -- atropine (the antidote) is an ALS/hospital intervention

Hypothermia

Hypothermia occurs when core body temperature falls below 95 degrees F (35 degrees C).

SeverityCore TemperatureSigns and Symptoms
Mild90-95 degrees F (32-35 degrees C)Shivering, poor coordination, slurred speech, confusion
Moderate82-90 degrees F (28-32 degrees C)Shivering stops, increasing confusion, drowsiness, cardiac dysrhythmias
Severe<82 degrees F (<28 degrees C)Unresponsive, no shivering, fixed dilated pupils, V-fib risk, appears dead

Hypothermia Treatment

  • Remove from cold environment
  • Remove wet clothing and cover with warm blankets
  • Handle the patient gently -- rough handling can trigger V-fib in severe hypothermia
  • Apply heat to the core (neck, armpits, groin) -- passive external rewarming
  • Administer warm, humidified oxygen if available
  • Do NOT rub extremities or apply direct heat to arms/legs
  • In severe hypothermia: "They're not dead until they're warm and dead" -- continue resuscitation

Hyperthermia

Heat Exhaustion vs. Heat Stroke

FeatureHeat ExhaustionHeat Stroke
Mental statusNormal or mild confusionAltered (confusion, seizures, coma)
SkinCool, pale, diaphoretic (sweaty)Hot, red; may be dry or wet
Core temp<104 degrees F (<40 degrees C)>104 degrees F (>40 degrees C)
SeverityUrgentLife-threatening emergency

Heat Stroke Treatment

  • Aggressive cooling is the priority
  • Move to cool environment, remove excess clothing
  • Apply cold packs to neck, armpits, groin (areas with large blood vessels)
  • Fan the patient while misting with water
  • Cold IV fluids (ALS)
  • Rapid transport

Drowning

  • Remove from water (ensure rescuer safety)
  • C-spine precautions if diving injury suspected
  • Priority is ventilation -- begin rescue breathing/BVM immediately
  • Do NOT attempt to drain water from lungs (abdominal thrusts are not effective)
  • Even if patient appears to recover, transport for observation (risk of delayed pulmonary edema)

Bites and Stings

Snake Bites

  • Keep patient calm and still (reduces venom spread)
  • Immobilize the affected extremity at or below heart level
  • Mark the edge of swelling with a pen and note the time
  • Do NOT apply a tourniquet, ice, or attempt to suck out venom
  • Transport to facility with antivenom capability

Spider Bites

  • Black widow: Severe muscle pain, abdominal rigidity, hypertension
  • Brown recluse: Initially painless, develops into necrotic wound over hours/days
  • Treatment: Clean wound, ice, pain management, transport

Marine Envenomation

  • Jellyfish: rinse with vinegar (acetic acid), remove tentacles with tweezers
  • Do NOT rinse with fresh water (can cause nematocyst discharge)
Test Your Knowledge

An unresponsive patient is found with a respiratory rate of 4, pinpoint pupils, and a syringe nearby. The EMT should FIRST:

A
B
C
D
Test Your Knowledge

The intranasal dose of naloxone (Narcan) for a suspected opioid overdose is:

A
B
C
D
Test Your Knowledge

Why is pulse oximetry unreliable in carbon monoxide poisoning?

A
B
C
D
Test Your Knowledge

A farmer is found in a field with excessive salivation, lacrimation, urination, and pinpoint pupils after spraying pesticides. This presentation is consistent with:

A
B
C
D
Test Your Knowledge

Which finding differentiates heat stroke from heat exhaustion?

A
B
C
D
Test Your Knowledge

When managing a severely hypothermic patient, why should the EMT handle the patient gently?

A
B
C
D
Test Your Knowledge

A near-drowning victim has been pulled from the water and is not breathing. After ensuring scene safety, the EMT should:

A
B
C
D
Test Your Knowledge

An important consideration when administering naloxone to a patient with suspected opioid overdose is that:

A
B
C
D
Test Your KnowledgeMatching

Match each poisoning or overdose type to its classic signs and symptoms:

Match each item on the left with the correct item on the right

1
Opioid overdose
2
Carbon monoxide poisoning
3
Organophosphate poisoning