Key Takeaways

  • Lymphedema management uses Complete Decongestive Therapy (CDT): manual lymphatic drainage, compression bandaging, exercise, and skin care
  • Diabetes effects on PT: Type 1 (insulin-dependent, autoimmune) and Type 2 (insulin resistance); exercise lowers blood glucose; monitor for hypoglycemia during exercise
  • Hypoglycemia signs during exercise: shakiness, sweating, confusion, pallor, tachycardia; treat with 15g fast-acting carbohydrate (Rule of 15)
  • Oncology rehab: exercise is safe and beneficial during/after cancer treatment; monitor for fatigue, bone metastases (fracture risk), neutropenia (infection risk), and thrombocytopenia (bleeding risk)
  • Osteoporosis: T-score of -1.0 to -2.5 is osteopenia; T-score below -2.5 is osteoporosis; weight-bearing and resistance exercises are recommended; avoid excessive spinal flexion
  • GI/GU considerations: pelvic floor dysfunction is treated with Kegel exercises, biofeedback, and behavioral training; urinary incontinence types include stress, urge, and mixed
  • Obstetric PT: diastasis recti screening, pelvic floor strengthening, exercise modifications by trimester, and postpartum rehabilitation
  • Metabolic syndrome: cluster of conditions including central obesity, hypertension, hyperglycemia, high triglycerides, and low HDL cholesterol
Last updated: February 2026

Other Body Systems

This section covers body systems beyond the primary musculoskeletal, neuromuscular, and cardiopulmonary domains. While individually representing smaller portions of the NPTE, these topics collectively account for 4-7% of the exam and often involve complex clinical scenarios.


Lymphedema Management

Lymphedema is chronic swelling caused by impaired lymphatic drainage. It is most commonly secondary to lymph node removal or radiation for cancer treatment.

Complete Decongestive Therapy (CDT) — Gold Standard

CDT has two phases:

Phase I: Intensive/Reductive Phase (2-4 weeks)

ComponentDescription
Manual Lymphatic Drainage (MLD)Gentle, rhythmic massage that redirects lymph fluid from congested to functional lymphatic pathways
Compression BandagingShort-stretch bandages applied in layers to maintain fluid reduction after MLD
Therapeutic ExerciseGentle, rhythmic exercises performed WITH compression to enhance lymph flow
Skin CareMeticulous skin hygiene to prevent infection (cellulitis is a major complication)

Phase II: Maintenance Phase (lifelong)

  • Custom-fitted compression garments (20-60 mmHg depending on severity)
  • Continued exercise and skin care
  • Self-MLD as needed
  • Garment replacement every 4-6 months

Contraindications to MLD:

  • Acute infection (cellulitis) in the affected limb
  • Active cancer in the lymphatic drainage area
  • Congestive heart failure (risk of fluid overload)
  • Deep vein thrombosis (DVT) in the affected limb

Diabetes and Exercise

Type 1 vs. Type 2 Diabetes

FeatureType 1Type 2
CauseAutoimmune destruction of pancreatic beta cellsInsulin resistance + relative insulin deficiency
OnsetUsually childhood/adolescenceUsually adulthood (but increasing in youth)
TreatmentInsulin requiredLifestyle modification, oral medications, may need insulin
% of Cases~5-10%~90-95%

Exercise Considerations for Diabetes

Benefits of exercise:

  • Lowers blood glucose (muscles uptake glucose without insulin during exercise)
  • Improves insulin sensitivity for 24-72 hours post-exercise
  • Reduces cardiovascular risk factors

Pre-exercise blood glucose guidelines:

  • <100 mg/dL: Consume 15-30g carbohydrate before exercising
  • 100-250 mg/dL: Safe range for exercise
  • >250 mg/dL with ketones: Do NOT exercise (risk of ketoacidosis)
  • >300 mg/dL without ketones: Use caution; may need to wait

Hypoglycemia Management (Rule of 15)

If blood glucose falls below 70 mg/dL:

  1. Consume 15 grams of fast-acting carbohydrate (4 oz juice, glucose tablets)
  2. Wait 15 minutes
  3. Recheck blood glucose
  4. Repeat if still below 70 mg/dL

Signs of Hypoglycemia: Shakiness, sweating, confusion, pallor, tachycardia, dizziness, irritability, hunger


Oncology Rehabilitation

Exercise During Cancer Treatment

Current evidence strongly supports exercise during and after cancer treatment:

  • Reduces cancer-related fatigue (most common side effect)
  • Improves physical function, quality of life, and psychological well-being
  • May reduce recurrence risk for certain cancers

Precautions by Lab Values

Lab ValueThresholdPrecaution
Hemoglobin<8 g/dLNo resistive exercise; limit to light activity
Platelets<50,000/mm3 (thrombocytopenia)Avoid activities with bleeding/bruising risk
Platelets<20,000/mm3Active ROM only; no resistance
WBC (ANC)<500/mm3 (severe neutropenia)Avoid group settings; strict infection control
Bone metastasesIdentified on imagingAvoid high-impact activities; fracture risk

Osteoporosis

DEXA Scan T-Score Interpretation

T-ScoreClassification
-1.0 and aboveNormal bone density
-1.0 to -2.5Osteopenia (low bone mass)
Below -2.5Osteoporosis
Below -2.5 with fractureSevere (established) osteoporosis

Exercise Recommendations

  • Weight-bearing exercise: Walking, jogging, stair climbing, dancing
  • Resistance training: Progressive strengthening with emphasis on back extensors
  • Balance training: Fall prevention is critical
  • Avoid: Excessive spinal flexion, high-impact activities in severe osteoporosis, trunk rotation with load

Pelvic Floor Dysfunction

Types of Urinary Incontinence

TypeMechanismPresentationPT Treatment
StressWeak pelvic floor muscles or urethral sphincterLeakage with cough, sneeze, laugh, exerciseKegel exercises, biofeedback, electrical stimulation
UrgeDetrusor overactivitySudden strong urge, unable to delay; frequencyBladder training, urgency suppression, timed voiding
MixedCombination of stress and urgeFeatures of bothCombined approach
OverflowIncomplete bladder emptyingDribbling, weak stream, frequent small volumesAddress underlying cause; may need catheterization
Test Your Knowledge

A patient with Type 2 diabetes has a pre-exercise blood glucose of 280 mg/dL with no ketones present. The PT should:

A
B
C
D
Test Your Knowledge

Which of the following is a component of Complete Decongestive Therapy (CDT) for lymphedema?

A
B
C
D
Test Your Knowledge

A patient with cancer has a platelet count of 35,000/mm3. The PT should:

A
B
C
D
Test Your Knowledge

A DEXA scan T-score of -2.8 indicates:

A
B
C
D
Test Your Knowledge

The Rule of 15 for managing hypoglycemia involves:

A
B
C
D
Test Your Knowledge

Which type of urinary incontinence is characterized by leakage with coughing, sneezing, or laughing?

A
B
C
D
Test Your Knowledge

A contraindication to manual lymphatic drainage (MLD) is:

A
B
C
D
Test Your Knowledge

For a patient with osteoporosis, which of the following exercises should be AVOIDED?

A
B
C
D