Key Takeaways

  • Health topics cover approximately 8 items (~13%) of the NEX Science section
  • Essential nutrients: carbohydrates, proteins, fats, vitamins, minerals, and water
  • Water-soluble vitamins (B, C) are not stored and need daily intake; fat-soluble vitamins (A, D, E, K) are stored in fat tissue
  • Infectious diseases are caused by pathogens: bacteria, viruses, fungi, and parasites
  • The immune system has two types of response: innate (nonspecific, immediate) and adaptive (specific, memory)
  • Communicable diseases spread person-to-person; non-communicable diseases (cancer, diabetes, heart disease) do not
  • Risk factors for chronic disease include poor diet, physical inactivity, smoking, excessive alcohol, and stress
  • Homeostasis is the body's ability to maintain stable internal conditions despite external changes
Last updated: February 2026

Health, Nutrition & Disease

Health topics account for approximately 8 items (~13%) of the NEX Science section. These questions bridge basic science knowledge with real-world health applications.


Essential Nutrients

NutrientFunctionSourcesDaily Need
CarbohydratesPrimary energy sourceGrains, fruits, vegetables45-65% of calories
ProteinsBuild/repair tissue, enzymes, immune functionMeat, fish, beans, dairy10-35% of calories
FatsEnergy storage, insulation, cell membranesOils, nuts, avocado, dairy20-35% of calories
VitaminsRegulate body processes, support immunityFruits, vegetables, dairyVaries by vitamin
MineralsBone health, fluid balance, nerve functionVegetables, dairy, meatVaries by mineral
WaterTransport, temperature regulation, digestionBeverages, foods~8 cups/day

Vitamins: Water-Soluble vs. Fat-Soluble

CategoryVitaminsKey Fact
Water-solubleB vitamins (B1, B2, B3, B5, B6, B7, B9, B12), Vitamin CNot stored; need daily intake; excess excreted in urine
Fat-solubleVitamins A, D, E, KStored in fat tissue and liver; can accumulate to toxic levels

Key vitamins for nursing:

VitaminFunctionDeficiency
Vitamin AVision, immune function, skinNight blindness
Vitamin B12Red blood cell formation, nerve functionPernicious anemia, neuropathy
Vitamin CCollagen synthesis, immune function, wound healingScurvy
Vitamin DCalcium absorption, bone healthRickets (children), osteomalacia (adults)
Vitamin KBlood clottingExcessive bleeding
Folic acid (B9)DNA synthesis, fetal developmentNeural tube defects in pregnancy
Iron (mineral)Oxygen transport in hemoglobinIron-deficiency anemia
Calcium (mineral)Bone/teeth, muscle contraction, nerve functionOsteoporosis

Disease Concepts

Communicable vs. Non-Communicable

TypeSpreadExamples
CommunicablePerson-to-person via pathogensInfluenza, COVID-19, tuberculosis, HIV
Non-communicableNot spread between people; caused by genetics, lifestyle, environmentHeart disease, diabetes, cancer, asthma

Types of Pathogens

PathogenDescriptionExample Diseases
BacteriaSingle-celled prokaryotes; some beneficial, some harmfulStrep throat, UTIs, tuberculosis
VirusesNon-living; require a host cell to reproduceInfluenza, COVID-19, HIV, measles
FungiCan be unicellular or multicellularAthlete's foot, yeast infections, ringworm
ParasitesOrganisms that live on/in a hostMalaria, tapeworms, lice

The Immune System

Response TypeSpeedSpecificityMemoryExamples
Innate (nonspecific)ImmediateGeneral (fights all pathogens)NoSkin barrier, inflammation, fever, phagocytes
Adaptive (specific)Slower (days)Targeted (specific pathogen)YesAntibodies, T cells, B cells

Vaccination stimulates the adaptive immune system to produce memory cells without causing disease, providing future protection.


Homeostasis

Homeostasis is the body's ability to maintain a stable internal environment despite changing external conditions.

Negative feedback loops (most common): The body detects a change and acts to reverse it.

  • Example: Body temperature rises → sweat glands activate → body cools down → sweating stops

Positive feedback loops (less common): The body amplifies a change until a process is complete.

  • Example: During labor, contractions stimulate oxytocin release → more contractions → continues until delivery

Chronic Disease Risk Factors

Risk FactorAssociated Conditions
SmokingLung cancer, COPD, heart disease, stroke
Physical inactivityObesity, type 2 diabetes, heart disease
Poor dietObesity, hypertension, type 2 diabetes
Excessive alcoholLiver disease, certain cancers, pancreatitis
ObesityType 2 diabetes, heart disease, joint problems
StressHypertension, immune suppression, mental health disorders
GeneticsVarious conditions; cannot be modified but can be managed
NLN NEX Science Section — Topic Distribution
Test Your Knowledge

Which of the following vitamins is fat-soluble?

A
B
C
D
Test Your Knowledge

What type of feedback loop is responsible for regulating body temperature?

A
B
C
D
Test Your Knowledge

Which pathogen requires a host cell to reproduce?

A
B
C
D
Test Your KnowledgeMulti-Select

Which of the following are functions of proteins in the body? (Select all that apply)

Select all that apply

Building and repairing tissues
Storing genetic information
Acting as enzymes to catalyze reactions
Primary source of quick energy
Transporting oxygen in the blood (hemoglobin)
Immune defense (antibodies)
Test Your KnowledgeFill in the Blank

The body's ability to maintain a stable internal environment despite changing external conditions is called _____.

Type your answer below

Test Your Knowledge

A deficiency in Vitamin C can lead to:

A
B
C
D
Test Your Knowledge

Which of the following diseases is classified as COMMUNICABLE (infectious)?

A
B
C
D
Test Your KnowledgeMatching

Match each vitamin deficiency to its associated condition.

Match each item on the left with the correct item on the right

1
Vitamin A deficiency
2
Vitamin C deficiency
3
Vitamin D deficiency
4
Vitamin B12 deficiency
5
Vitamin K deficiency
Test Your Knowledge

The innate immune system differs from the adaptive immune system because the innate system:

A
B
C
D
Test Your Knowledge

During a positive feedback loop:

A
B
C
D
Test Your KnowledgeFill in the Blank

The fat-soluble vitamins are A, D, E, and _____.

Type your answer below