Key Takeaways

  • The adult skeleton has 206 bones, divided into the axial skeleton (80 bones) and appendicular skeleton (126 bones)
  • Bones provide support, protection, movement (with muscles), mineral storage (calcium/phosphorus), and blood cell production (hematopoiesis)
  • Joints (articulations) are classified by movement: synarthrosis (immovable), amphiarthrosis (slightly movable), diarthrosis (freely movable)
  • The three types of muscle tissue are skeletal (voluntary, striated), cardiac (involuntary, striated), and smooth (involuntary, non-striated)
  • Skeletal muscles produce movement through contraction; they work in antagonistic pairs (biceps/triceps)
  • The integumentary system includes skin, hair, nails, and glands; skin is the largest organ of the body
  • The skin has three layers: epidermis (outermost, protection), dermis (middle, blood vessels and nerves), hypodermis (deepest, fat storage)
  • Burns are classified by depth: first-degree (epidermis), second-degree (epidermis + dermis), third-degree (all layers)
Last updated: February 2026

Skeletal, Muscular & Integumentary Systems

These three systems work together to provide structure, protection, movement, and defense for the body.


Skeletal System

The adult human skeleton contains 206 bones divided into two divisions:

DivisionBonesIncludes
Axial skeleton80Skull (22), vertebral column (26), thoracic cage (25), hyoid (1), auditory ossicles (6)
Appendicular skeleton126Upper limbs (64), lower limbs (62), pelvic girdle, pectoral girdle

Functions of Bones

  1. Support — framework for the body
  2. Protection — skull protects the brain, ribs protect the heart and lungs
  3. Movement — serve as levers for muscle attachment
  4. Mineral storage — calcium and phosphorus
  5. Blood cell production — hematopoiesis occurs in red bone marrow
  6. Energy storage — yellow bone marrow stores fat

Types of Bones

TypeShapeExamples
Long bonesLonger than wideFemur, humerus, tibia
Short bonesCube-shapedCarpals (wrist), tarsals (ankle)
Flat bonesThin, flatSkull, sternum, ribs, scapula
Irregular bonesComplex shapesVertebrae, hip bones
Sesamoid bonesWithin tendonsPatella (kneecap)

Joints (Articulations)

ClassificationMovementExample
SynarthrosisImmovableSkull sutures
AmphiarthrosisSlightly movablePubic symphysis, intervertebral discs
Diarthrosis (synovial)Freely movableKnee, shoulder, hip, elbow

Types of synovial joints: hinge (elbow, knee), ball-and-socket (hip, shoulder), pivot (atlas-axis), saddle (thumb), gliding (wrist), condyloid (wrist-forearm)


Muscular System

The body has over 600 skeletal muscles. There are three types of muscle tissue:

TypeControlAppearanceLocation
SkeletalVoluntaryStriated (striped)Attached to bones
CardiacInvoluntaryStriated with intercalated discsHeart only
SmoothInvoluntaryNon-striated (spindle-shaped)Organs, blood vessels, GI tract

How Muscles Work

  • Muscles produce movement by contracting (shortening)
  • Muscles work in antagonistic pairs: when one contracts, the other relaxes
    • Example: Biceps (flexor) contracts → forearm bends; Triceps (extensor) contracts → forearm extends
  • Origin: The fixed attachment point (does not move)
  • Insertion: The movable attachment point (moves during contraction)

Types of Muscle Contractions

  • Isotonic: Muscle length changes (lifting a weight)
  • Isometric: Muscle length stays the same but tension increases (pushing against a wall)

Integumentary System

The skin is the largest organ of the body, covering approximately 20 square feet in adults.

Three Layers of Skin

LayerDescriptionContains
EpidermisOutermost layer; avascular (no blood vessels)Keratinocytes, melanocytes, Langerhans cells
DermisMiddle layer; vascularBlood vessels, nerves, hair follicles, sweat glands, sebaceous glands
Hypodermis (subcutaneous)Deepest layerAdipose tissue (fat), larger blood vessels

Functions of Skin

  1. Protection — barrier against pathogens, UV radiation, and chemicals
  2. Temperature regulation — sweating cools; vasoconstriction conserves heat
  3. Sensation — receptors for touch, pain, temperature, pressure
  4. Vitamin D synthesis — UV light converts cholesterol to vitamin D
  5. Excretion — sweat removes small amounts of waste

Burn Classification

DegreeDepthAppearancePain
First-degree (superficial)Epidermis onlyRed, dry, no blistersPainful
Second-degree (partial-thickness)Epidermis + dermisRed, blistered, moistVery painful
Third-degree (full-thickness)All layers + possibly deeperWhite, charred, leatheryPainless (nerve damage)
Test Your Knowledge

How many bones are in the adult human skeleton?

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B
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D
Test Your Knowledge

Which type of muscle tissue is involuntary AND striated?

A
B
C
D
Test Your Knowledge

A third-degree burn is characterized by:

A
B
C
D
Test Your KnowledgeFill in the Blank

The process of blood cell production in red bone marrow is called _____.

Type your answer below

Test Your KnowledgeMatching

Match each muscle type to its key characteristics.

Match each item on the left with the correct item on the right

1
Skeletal muscle
2
Cardiac muscle
3
Smooth muscle
Test Your Knowledge

Which layer of skin contains blood vessels, nerves, and hair follicles?

A
B
C
D