Key Takeaways

  • The surgical prep removes transient microorganisms and reduces resident flora on the patient's skin
  • Common antiseptic agents include chlorhexidine gluconate (CHG), povidone-iodine (Betadine), and isopropyl alcohol
  • CHG-alcohol combination is preferred for most surgical preps due to superior antimicrobial activity
  • The prep is performed in a circular motion from the incision site outward (clean to dirty)
  • The prepped sponge should never return to an area already cleaned (unidirectional)
  • A contaminated area (e.g., stoma, wound) is prepped LAST with a separate sponge
  • Draping creates a sterile field around the operative site using sterile towels and drape sheets
  • Drapes are placed from the operative site outward and should not be repositioned once placed
Last updated: February 2026

Surgical Skin Prep & Draping

The surgical skin preparation and draping are critical steps in preventing surgical site infections (SSIs). The surgical technologist may assist with or perform the prep under the direction of the circulating nurse or surgeon.


Antiseptic Agents for Surgical Prep

AgentTrade NamePropertiesConsiderations
Chlorhexidine gluconate (CHG)HibiclensBroad-spectrum, residual activity, not inactivated by bloodDo NOT use near eyes, ears, or mucous membranes
CHG + Isopropyl alcoholChloraPrepSuperior antimicrobial activity, rapid onsetFlammable — must dry completely before draping
Povidone-iodineBetadineBroad-spectrum, safe for mucous membranesInactivated by blood and organic matter; check iodine allergy
Iodine + alcoholDuraPrepRapid onset, residual activityFlammable; not for mucous membranes
Isopropyl alcohol (70%)Rapid bactericidal actionFlammable; no residual activity

Current Evidence: The CHG-alcohol combination (ChloraPrep) is preferred for most surgical preps because it has the broadest antimicrobial spectrum, the fastest onset, and the longest residual activity. However, it is contraindicated near the eyes, ears, and mucous membranes, where povidone-iodine should be used instead.


Surgical Prep Technique

Principles

  1. Clean to dirty: Begin at the incision site and work outward in expanding circles
  2. Never return the sponge to a previously prepped area — discard and use a new sponge
  3. Prep contaminated areas last: If a stoma, open wound, or drain is present, prep it with a separate sponge after the clean area
  4. Allow to dry completely: Especially important for alcohol-based preps (fire risk)
  5. Extend the prep beyond the anticipated drape field to allow for incision extension if needed

Special Prep Considerations

SituationModification
Traumatic open woundPrep around the wound, then prep the wound last
Stoma presentCover stoma, prep surrounding skin, then prep stoma with separate supplies
Eye surgeryUse povidone-iodine (Betadine) only — NO chlorhexidine or alcohol near eyes
Ear surgeryAvoid CHG — ototoxic if it enters the middle ear
Skin graft donor sitePrep donor site first (cleaner), then recipient site
Extremity prepLimb is elevated and held by assistant; prep circumferentially

Draping Principles

Sterile draping creates the sterile field around the operative site:

  • Drapes are applied from the operative site outward (closest to incision first, then periphery)
  • Never reach across an unsterile area to place a drape
  • Drapes should not be repositioned once placed — if a drape is placed incorrectly, it may be covered with another drape but not moved toward the incision
  • Towel clips secure drapes; penetrating towel clips that pierce the skin are considered contaminated once removed
  • Fenestrated drapes (drapes with a window/opening) are placed so the window aligns with the incision site
  • All team members should cuff the drapes over their gloved hands while placing them to prevent contamination
Test Your Knowledge

Which antiseptic agent is preferred for most surgical skin preparations?

A
B
C
D
Test Your Knowledge

During a surgical prep, the scrub sponge should move in which pattern?

A
B
C
D
Test Your Knowledge

A patient is scheduled for eye surgery. Which antiseptic should be used for the surgical prep?

A
B
C
D
Test Your Knowledge

If a sterile drape is placed too low and partially covers the incision site, the surgical technologist should:

A
B
C
D
Test Your KnowledgeFill in the Blank

Alcohol-based surgical prep solutions are flammable and must _____ completely before draping and the use of electrosurgery.

Type your answer below