Key Takeaways

  • During a seizure: protect from injury, turn to side, do NOT restrain or insert objects in mouth, time the seizure
  • Status epilepticus: seizure lasting > 5 minutes or multiple seizures without regaining consciousness; medical emergency
  • First-line treatment for status epilepticus: IV benzodiazepines (lorazepam or diazepam)
  • Post-seizure (postictal) care: maintain airway, orient patient, monitor vitals, document duration and characteristics
  • Seizure precautions include padded side rails, suction at bedside, oxygen available, bed in lowest position
Last updated: January 2026

Neurological Conditions: Seizures

Seizures occur when there is abnormal, excessive electrical activity in the brain. They can range from barely noticeable to severe convulsions. Nurses must know how to protect patients during seizures and recognize when seizures become medical emergencies.

Pathophysiology

Seizures result from:

  • Sudden, abnormal electrical discharge in neurons
  • May be localized (focal) or generalized throughout the brain
  • Causes temporary changes in consciousness, movement, sensation, or behavior

Types of Seizures

Focal (Partial) Seizures - Start in one area:

TypeCharacteristics
Simple FocalNo loss of consciousness; motor, sensory, or autonomic symptoms
Complex FocalImpaired consciousness; automatisms (lip smacking, picking at clothes)
Focal to Bilateral Tonic-ClonicStarts focal, spreads to generalized

Generalized Seizures - Both hemispheres from onset:

TypeCharacteristics
Absence (Petit Mal)Brief staring spells (seconds); common in children; no postictal phase
Tonic-Clonic (Grand Mal)Loss of consciousness, stiffening (tonic), rhythmic jerking (clonic)
MyoclonicBrief muscle jerks; may occur in clusters
Atonic (Drop Attacks)Sudden loss of muscle tone; patient falls
TonicSustained muscle stiffening
ClonicRhythmic jerking movements

Causes of Seizures

In Patients WITH Epilepsy:

  • Medication non-compliance (most common)
  • Sleep deprivation
  • Illness, fever, infection
  • Alcohol or drug use
  • Missed meals (hypoglycemia)
  • Stress
  • Flashing lights (photosensitive epilepsy)

In Patients WITHOUT Epilepsy:

  • Head trauma
  • Stroke
  • Brain tumor
  • Metabolic disturbances (hypoglycemia, hyponatremia, hypoxia)
  • Drug toxicity or withdrawal
  • High fever (febrile seizures in children)
  • Eclampsia (pregnancy)
  • Alcohol withdrawal

Phases of a Generalized Tonic-Clonic Seizure

1. Aura (Prodromal Phase)

  • Warning sign before seizure
  • Not all patients experience an aura
  • May include visual, auditory, or olfactory sensations
  • Allows patient to get to safety

2. Tonic Phase (10-20 seconds)

  • Loss of consciousness
  • Muscles stiffen
  • May have a cry (air forced through vocal cords)
  • Falls if standing
  • May become cyanotic (not breathing)

3. Clonic Phase (30-60 seconds)

  • Rhythmic muscle jerking
  • May bite tongue
  • Excessive salivation
  • Loss of bladder/bowel control possible

4. Postictal Phase (Minutes to hours)

  • Gradual return of consciousness
  • Confusion, disorientation
  • Fatigue, sleepiness
  • Headache
  • Muscle soreness
  • No memory of seizure

Nursing Care During a Seizure

The Priority is SAFETY

Do:

  • Stay with the patient - Call for help but do not leave
  • Time the seizure - Duration is critical information
  • Protect from injury:
    • Lower to floor if standing
    • Move furniture and hard objects away
    • Place padding under head (pillow, folded blanket)
  • Turn to side (recovery position) - Maintains airway, prevents aspiration
  • Loosen restrictive clothing - Ties, collars, tight clothing
  • Maintain airway - Suction secretions after seizure if needed

Do NOT:

  • Do NOT restrain - Can cause injury during forceful movements
  • Do NOT insert anything in mouth - No tongue blades, fingers, or airways
    • Cannot "swallow tongue"
    • Forcing mouth open can break teeth, injure jaw
  • Do NOT give oral medications or fluids during seizure
  • Do NOT leave patient unattended

Exam Tip: The most common incorrect answer choice is "insert a padded tongue blade." NEVER insert objects in the mouth during a seizure!


Post-Seizure (Postictal) Care

After the seizure ends:

  1. Maintain airway - Keep on side, suction if needed
  2. Assess breathing - Apply oxygen if needed
  3. Check for injuries - Tongue lacerations, head trauma, fractures
  4. Provide orientation - Reorient patient gently; speak calmly
  5. Allow rest - Patient will be exhausted
  6. Document thoroughly:
    • Time seizure started and ended
    • Behavior before seizure (aura)
    • Body parts involved, progression
    • Loss of consciousness
    • Postictal state and duration

Status Epilepticus

Definition: A seizure lasting longer than 5 minutes OR two or more seizures without regaining consciousness between them.

This is a MEDICAL EMERGENCY

Why It's Dangerous

  • Prolonged seizure activity causes brain damage
  • Hypoxia from impaired breathing
  • Hyperthermia from muscle activity
  • Metabolic acidosis
  • Can be fatal

Treatment of Status Epilepticus

Priority Order:

  1. Maintain airway - May need intubation
  2. Oxygen - High flow
  3. IV access - Establish immediately
  4. Check blood glucose - Treat hypoglycemia with D50W
  5. First-line medications:
MedicationDoseNotes
Lorazepam (Ativan)4 mg IVPreferred first-line; may repeat x1
Diazepam (Valium)10 mg IVAlternative; shorter duration
Midazolam (Versed)10 mg IMIf no IV access
  1. Second-line if benzodiazepines fail:

    • Fosphenytoin or phenytoin IV
    • Levetiracetam (Keppra) IV
    • Valproate IV
  2. Refractory status epilepticus:

    • Propofol, pentobarbital, or ketamine infusion
    • ICU admission required

Seizure Precautions

For patients at risk for seizures:

PrecautionRationale
Padded side railsPrevents injury during seizure
Bed in lowest positionReduces fall injury
Suction at bedsideClears secretions post-seizure
Oxygen at bedsideAvailable for post-seizure hypoxia
IV accessReady for emergency medications
Call light within reachPatient can summon help
Remove sharp/hard objectsPrevents injury

Antiepileptic Drugs (AEDs)

Common medications for seizure prevention:

MedicationKey Points
Phenytoin (Dilantin)Therapeutic level 10-20 mcg/mL; causes gingival hyperplasia
Carbamazepine (Tegretol)Monitor blood counts; many drug interactions
Valproic Acid (Depakote)Weight gain, hair loss; contraindicated in pregnancy
Levetiracetam (Keppra)Few drug interactions; well tolerated
Lamotrigine (Lamictal)Risk of Stevens-Johnson syndrome

Patient Education:

  • Take medications as prescribed; do not skip doses
  • Do not stop medications abruptly (can cause seizures)
  • Avoid alcohol
  • Get adequate sleep
  • Know triggers and avoid them
  • Wear medical identification

Febrile Seizures in Children

  • Occur with fever in children 6 months to 5 years
  • Usually benign; most do not develop epilepsy
  • Manage fever with acetaminophen or ibuprofen
  • Tepid sponge bath (not ice water)
  • Education for parents on seizure first aid

Key Points for the NCLEX

  • DO NOT restrain during seizure
  • DO NOT insert anything in mouth
  • Turn to side to protect airway
  • Time the seizure - critical documentation
  • Status epilepticus = seizure > 5 minutes = emergency
  • Lorazepam IV is first-line for status epilepticus
  • Seizure precautions: padded rails, suction, oxygen, bed low
  • Postictal: patient is confused and exhausted; orient gently
  • Phenytoin: watch for gingival hyperplasia, therapeutic level 10-20 mcg/mL
Test Your Knowledge

A patient begins having a tonic-clonic seizure. What is the priority nursing action?

A
B
C
D
Test Your Knowledge

A seizure has lasted for 7 minutes. What condition does this represent?

A
B
C
D
Test Your Knowledge

Which medication is first-line treatment for status epilepticus?

A
B
C
D
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