Unit Dose Packaging

Unit dose packaging is a medication distribution system where each individual dose of a medication is packaged separately in its own labeled container, ready for direct administration to the patient without further measurement or preparation.

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Exam Tip

Unit dose = single dose per package, standard in hospitals. Pharmacy technicians repackage bulk meds into unit doses and stock ADCs. Each unit dose must be labeled with drug, strength, lot, and expiration.

What Is Unit Dose Packaging?

Unit dose packaging is the standard medication distribution system used in hospitals and institutional pharmacy settings. Each package contains exactly one dose of medication in a ready-to-administer form, clearly labeled with the drug name, strength, lot number, and expiration date.

Unit Dose vs. Multi-Dose Packaging

FeatureUnit DoseMulti-Dose
ContentsSingle dose per packageMultiple doses per container
SettingHospital/institutionalRetail/community
MeasurementPre-measured, no calculation neededMay require measuring
WasteMinimal (dose-specific)Potential for waste
Error reductionHighest safety (barcode scannable)Relies on measuring accuracy
Cost per doseHigher packaging costLower packaging cost
ExamplesBlister packs, syringes, vialsBottles of 100/500 tablets

Types of Unit Dose Packaging

TypeDescriptionExample
Blister packTablet/capsule sealed in individual plastic/foil cavityMost common for oral solids
Unit-of-usePre-counted for complete course of therapyZ-pack (azithromycin)
Oral liquid unit dosePre-measured liquid in cup or syringe10 mL oral suspension
Injectable unit dosePre-filled syringe or single-use vialEnoxaparin pre-filled syringe
Repackaged unit dosePharmacy repackages bulk into unit dosesRobot-packaged strip packs

Unit Dose in Automated Dispensing Cabinets (ADCs)

FeatureDescription
StockingPharmacy fills ADC with unit dose packages
DispensingNurse selects patient/drug; drawer opens with unit dose
Barcode verificationUnit dose barcode scanned at bedside for verification
Inventory trackingADC tracks quantities and triggers refill alerts
Override accessEmergency doses available before pharmacist review

Benefits of Unit Dose Systems

  • Reduces medication errors (right drug, right dose)
  • Enables barcode medication administration (BCMA)
  • Decreases nursing time in medication preparation
  • Improves inventory control and billing accuracy
  • Reduces medication waste and diversion risk
  • Meets Joint Commission and state BOP standards

Pharmacy Technician's Role

  • Repackaging bulk medications into unit dose form
  • Stocking automated dispensing cabinets
  • Checking expiration dates during restocking
  • Verifying correct medications loaded into correct ADC pockets
  • Maintaining repackaging logs with lot numbers and BUDs

Exam Alert

Unit dose systems are tested in the Dispensing Process domain. Know that unit dose = one dose per package, it is the standard in institutional pharmacy, and that pharmacy technicians play a key role in repackaging and ADC management.

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