Drug Utilization Review (DUR)

Drug utilization review (DUR) is a systematic process of evaluating prescription drug use to ensure medications are used appropriately, safely, and effectively, as mandated by OBRA-90 for Medicaid patients.

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Exam Tip

Three types of DUR: prospective (before dispensing), concurrent (during therapy), retrospective (after). OBRA-90 mandates prospective DUR for Medicaid patients. Technicians refer DUR alerts to the pharmacist.

What Is Drug Utilization Review?

Drug utilization review (DUR) is a quality assurance program that evaluates prescription drug therapy before, during, and after dispensing. OBRA-90 established Medicaid DUR requirements, implemented through state plans with specified exceptions. Prospective review occurs before dispensing, while retrospective review examines prior utilization. State laws and pharmacy practice often extend safety screening beyond Medicaid.

Types of DUR

TypeWhen It OccursDescription
Prospective DURBefore dispensingReal-time screening at point of sale for interactions, duplications, allergies
Concurrent DURDuring therapyOngoing monitoring of drug therapy while patient is taking medication
Retrospective DURAfter dispensingAnalysis of prescribing patterns and outcomes over time

What Prospective DUR Screens For

Alert TypeExample
Drug-drug interactionsWarfarin + aspirin (increased bleeding risk)
Drug-allergy conflictsPenicillin prescribed to penicillin-allergic patient
Therapeutic duplicationTwo SSRIs prescribed simultaneously
Incorrect dosageDose exceeds maximum recommended
Drug-disease contraindicationNSAID prescribed to patient with renal failure
Drug-age precautionBenzodiazepine prescribed to elderly patient (Beers Criteria)
Pregnancy-related riskA drug with embryo-fetal toxicity prescribed to a patient who may be pregnant; pharmacist evaluates the individual situation
Over/underutilizationRefilling too early or too late
Duration of therapyAntibiotic prescribed for longer than recommended

OBRA-90 Requirements

RequirementDetails
Prospective DURMust be performed before dispensing for Medicaid patients
Patient counselingPharmacist offers counseling under applicable state standards; the federal rule is not limited to new prescriptions
Record keepingPatient profiles must be maintained
Applies toMedicaid covered outpatient drug use, subject to the federal exceptions and state implementation rules

Pharmacy Technician's Role in DUR

  • Entering prescription data accurately to trigger appropriate DUR alerts
  • Recognizing DUR alerts flagged by the computer system
  • Referring DUR alerts to the pharmacist for clinical review
  • Documenting pharmacist override decisions

Exam Alert

DUR is a key topic in the ExCPT Laws, Dispensing Process, and Medication and Patient Safety and Quality Assurance domains. Know the three types (prospective, concurrent, retrospective), that OBRA-90 mandates prospective DUR for Medicaid, and that pharmacy technicians must refer all DUR alerts to the pharmacist for resolution.

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